Stereotactic Body Radiotherapy for Oligometastatic Disease in Non-small Cell Lung Cancer

被引：26

作者：

Wujanto, Caryn ^{[1
]}

Vellayappan, Balamurugan ^{[1
]}

Siva, Shankar ^{[2
]}

Louie, Alexander V. ^{[3
]}

Guckenberger, Matthias ^{[4
]}

Slotman, Ben J. ^{[5
]}

Onishi, Hiroshi ^{[6
]}

Nagata, Yasushi ^{[7
]}

Liu, Mitchell ^{[8
]}

Lo, Simon S. ^{[9
]}

机构：

[1] Natl Univ Hlth Syst, Natl Univ Canc Inst Singapore, Dept Radiat Oncol, Singapore, Singapore

[2] Univ Melbourne, Div Radiat Oncol & Canc Imaging, Peter MacCallum Canc Ctr, Melbourne, Vic, Australia

[3] Univ Toronto, Dept Radiat Oncol, Sunnybrook Hlth Sci Ctr, Toronto, ON, Canada

[4] Univ Hosp Zurich, Dept Radiat Oncol, Zurich, Switzerland

[5] Vrije Univ Amsterdam, Amsterdam Univ Med Ctr, Dept Radiat Oncol, Amsterdam, Netherlands

[6] Univ Yamanashi, Dept Radiol, Kofu, Yamanashi, Japan

[7] Hiroshima Univ, Grad Sch Biomed Sci, Dept Radiat Oncol, Hiroshima, Japan

[8] British Columbia Canc Agcy, Vancouver Ctr, Dept Radiat Oncol, Vancouver, BC, Canada

[9] Univ Washington, Sch Med, Dept Radiat Oncol, Seattle, WA 98195 USA

来源：

FRONTIERS IN ONCOLOGY | 2019年 / 9卷

关键词：

stereotactic body radiotherapy; non-small cell lung cancer; lung cancer; oligometastases; oligometastatic disease; 1ST-LINE SYSTEMIC THERAPY; RADIATION-THERAPY; CLINICAL-OUTCOMES; BRAIN METASTASES; PHASE-II; SURVIVAL; TRIAL; RADIOSURGERY; RECURRENCE; MANAGEMENT;

D O I：

10.3389/fonc.2019.01219

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Metastatic non-small cell lung cancer (NSCLC) is associated with a limited survival when treated with palliative intent platinum-based chemotherapy alone. Recent advances in imaging and therapeutic strategy have identified a subset of patients with limited metastases who may benefit from early local ablative therapy with either surgery or radiotherapy, in addition to standard treatment. Stereotactic body radiotherapy (SBRT) is increasingly used in the treatment of extra-cranial oligometastatic NSCLC (OM-NSCLC) due its non-invasive conduct and ability to deliver high doses. Clinical evidence supporting the use of SBRT in OM-NSCLC is emerging and consistently demonstrates significant benefit in local control and progression-free survival. Here, we discuss the definition of oligometastases (OM), review current available data on SBRT treatment in extra-cranial OM-NSCLC including evidence for site-specific SBRT in lung, liver, and adrenal metastases.

引用

页数：8

共 54 条

[1] Radiosensitivity Differences Between Liver Metastases Based on Primary Histology Suggest Implications for Clinical Outcomes After Stereotactic Body Radiation Therapy [J].

Ahmed, Kamran A. ;

Caudell, Jimmy J. ;

El-Haddad, Ghassan ;

Berglund, Anders E. ;

Welsh, Eric A. ;

Yue, Binglin ;

Hoffe, Sarah E. ;

Naghavi, Arash O. ;

Abuodeh, Yazan A. ;

Frakes, Jessica M. ;

Eschrich, Steven A. ;

Torres-Roca, Javier F. .

INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2016, 95 (05) :1399-1404

[2] SURVIVAL DETERMINANTS IN EXTENSIVE-STAGE NON-SMALL-CELL LUNG-CANCER - THE SOUTHWEST-ONCOLOGY-GROUP EXPERIENCE [J].

ALBAIN, KS ;

CROWLEY, JJ ;

LEBLANC, M ;

LIVINGSTON, RB .

JOURNAL OF CLINICAL ONCOLOGY, 1991, 9 (09) :1618-1626

[3] The SBRT database initiative of the German Society for Radiation Oncology (DEGRO): patterns of care and outcome analysis of stereotactic body radiotherapy (SBRT) for liver oligometastases in 474 patients with 623 metastases [J].

Andratschke, N. ;

Alheid, H. ;

Allgaeuer, M. ;

Becker, G. ;

Blanck, O. ;

Boda-Heggemann, J. ;

Brunner, T. ;

Duma, M. ;

Gerum, S. ;

Guckenberger, M. ;

Hildebrandt, G. ;

Klement, R. J. ;

Lewitzki, V. ;

Ostheimer, C. ;

Papachristofilou, A. ;

Petersen, C. ;

Schneider, T. ;

Semrau, R. ;

Wachter, S. ;

Habermehl, D. .

BMC CANCER, 2018, 18

[4] Whole brain radiation therapy with or without stereotactic radiosurgery boost for patients with one to three brain metastases: phase III results of the RTOG 9508 randomised trial [J].

Andrews, DW ;

Scott, CB ;

Sperduto, PW ;

Flanders, AE ;

Gaspar, LE ;

Schell, MC ;

Werner-Wasik, M ;

Demas, W ;

Ryu, J ;

Bahary, JP ;

Souhami, L ;

Rotman, M ;

Mehta, MP ;

Curran, WJ .

LANCET, 2004, 363 (9422) :1665-1672

[5] An Individual Patient Data Metaanalysis of Outcomes and Prognostic Factors After Treatment of Oligometastatic Non-Small-Cell Lung Cancer [J].

Ashworth, Allison B. ;

Senan, Suresh ;

Palma, David A. ;

Riquet, Marc ;

Ahn, Yong Chan ;

Ricardi, Umberto ;

Congedo, Maria T. ;

Gomez, Daniel R. ;

Wright, Gavin M. ;

Melloni, Giulio ;

Milano, Michael T. ;

Sole, Claudio V. ;

De Pas, Tommaso M. ;

Carter, Dennis L. ;

Warner, Andrew J. ;

Rodrigues, George B. .

CLINICAL LUNG CANCER, 2014, 15 (05) :346-355

[6] Pembrolizumab After Completion of Locally Ablative Therapy for Oligometastatic Non-Small Cell Lung Cancer: A Phase 2 Trial [J].

Bauml, Joshua M. ;

Mick, Rosemarie ;

Ciunci, Christine ;

Aggarwal, Charu ;

Davis, Christiana ;

Evans, Tracey ;

Deshpande, Charuhas ;

Miller, Linda ;

Patel, Pooja ;

Alley, Evan ;

Knepley, Christina ;

Mutale, Faith ;

Cohen, Roger B. ;

Langer, Corey J. .

JAMA ONCOLOGY, 2019, 5 (09) :1283-1290

[7] Radiotherapy for Oligometastatic Lung Cancer [J].

Bergsma, Derek P. ;

Salama, Joseph K. ;

Singh, Deepinder P. ;

Chmura, Steven J. ;

Milano, Michael T. .

FRONTIERS IN ONCOLOGY, 2017, 7

[8] Robot-assisted Extracranial Stereotactic Radiotherapy of Adrenal Metastases in Oligometastatic Non-small Cell Lung Cancer [J].

Celik, Eren ;

Semrau, Robert ;

Baues, Christian ;

Trommer-Nestler, Maike ;

Baus, Wolfgang ;

Marnitz, Simone .

ANTICANCER RESEARCH, 2017, 37 (09) :5285-5291

[9] Comparison of Local Control of Brain Metastases With Stereotactic Radiosurgery vs Surgical Resection A Secondary Analysis of a Randomized Clinical Trial [J].

Churilla, Thomas M. ;

Chowdhury, Imran H. ;

Handorf, Elizabeth ;

Collette, Laurence ;

Collette, Sandra ;

Dong, Yanqun ;

Alexander, Brian M. ;

Kocher, Martin ;

Soffietti, Riccardo ;

Claus, Elizabeth B. ;

Weiss, Stephanie E. .

JAMA ONCOLOGY, 2019, 5 (02) :243-247

[10] Phase II study of stereotactic body radiotherapy to primary tumor and metastatic locations in oligometastatic nonsmall-cell lung cancer patients [J].

Collen, C. ;

Christian, N. ;

Schallier, D. ;

Meysman, M. ;

Duchateau, M. ;

Storme, G. ;

De Ridder, M. .

ANNALS OF ONCOLOGY, 2014, 25 (10) :1954-1959

← 1 2 3 4 5 6 →