Phytic acid: Blessing in disguise, a prime compound required for both plant and human nutrition

被引:136
作者
Kumar, Awadhesh [1 ]
Singh, Brajesh [2 ]
Raigond, Pinky [2 ]
Sahu, Chandrasekhar [3 ]
Mishra, Udit Nandan [3 ]
Sharma, Srigopal [4 ]
Lal, Milan Kumar [2 ,5 ]
机构
[1] ICAR Natl Rice Res Inst ICAR NRRI, Div Crop Physiol & Biochem, Cuttack 753006, Odisha, India
[2] ICAR Cent Potato Res Inst ICAR CPRI, Div Crop Physiol Biochem & Postharvest Technol, Shimla 171001, Himachal Prades, India
[3] Centurion Univ Technol & Management, MS Swaminathan Sch Agr, Parlakhemundi 761211, Odisha, India
[4] Govind Ballabh Pant Univ Agr & Technol, Pantnagar, Uttarakhand, India
[5] ICAR Indian Agr Res Inst, Div Plant Physiol, New Delhi 110012, India
关键词
Phytic acid; Health benefit; Antidiabetic; Antioxidant; Antimicrobial agent; Food processing; PHYTATE REDUCTION; ZINC; SEED; ACCUMULATION; SERUM; IRON; BIOAVAILABILITY; MYOINOSITOL; ABSORPTION; SOAKING;
D O I
10.1016/j.foodres.2021.110193
中图分类号
TS2 [食品工业];
学科分类号
0832 ;
摘要
Phytic acid (PA), [myo-inositol 1,2,3,4,5,6-hexakisphosphate] is the principal storage compound of phosphorus (P) and account for 65%?85% of the seeds total P. The negative charge on PA attracts and chelates metal cations resulting in a mixed insoluble salt, phytate. Phytate contains six negatively charged ions, chelates divalent cations such as Fe2+, Zn2+, Mg2+, and Ca2+ rendering them unavailable for absorption by monogastric animals. This may lead to micronutrient deficiencies in humans since they lack the enzyme phytase that hydrolyzes phytate and releases the bound micronutrients. There are two main concerns about the presence of PA in human diet. The first is its negative impact on the bioavailability of several minerals and the second is the evidence of PA inhibiting various proteases essential for protein degradation and the subsequent digestion in stomach and small intestine. The beneficial role of PA has been underestimated due to its distinct negative consequences. PA is reported to be a potent natural plant antioxidant which plays a protective role against oxidative stress in seeds and preventive role in various human diseases. Recently beneficial roles of PA as an antidiabetic and antibacterial agent has been reported. Thus, the development of grains with low-PA and modified distribution pattern can be achieved through fine-tuning of its content in the seeds.
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页数:11
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