Costs of Workplace Productivity Loss in Patients With Fibrotic Interstitial Lung Disease

被引:21
作者
Algamdi, Mohmmed [1 ,2 ,3 ]
Sadatsafavi, Mohsen [4 ]
Fisher, Jolene [5 ]
Morisset, Julie [6 ]
Johannson, Kerri [7 ]
Fell, Charlene [7 ]
Kolb, Martin [8 ]
Manganas, Helene [6 ]
Cox, Gerard [8 ]
Gershon, Andrea [9 ]
Halayko, Andrew [10 ,11 ,12 ]
Hambly, Nathan [8 ]
Khalil, Nasreen [1 ]
Shapera, Shane [5 ]
To, Teresa [13 ]
Wilcox, Pearce [1 ]
Guler, Sabina [1 ,2 ]
Ryerson, Christopher [1 ,2 ]
机构
[1] Univ British Columbia, Dept Med, Vancouver, BC, Canada
[2] St Pauls Hosp, Ctr Heart Lung Innovat, Vancouver, BC, Canada
[3] King Fahad Med City, Dept Pulm & Crit Care Med, Riyadh, Saudi Arabia
[4] Univ British Columbia, Fac Pharmaceut Sci, Resp Evaluat Sci Program, Vancouver, BC, Canada
[5] Univ Toronto, Dept Med, Toronto, ON, Canada
[6] Ctr Hosp Univ Montreal, Dept Med, Montreal, PQ, Canada
[7] Univ Calgary, Dept Med, Calgary, AB, Canada
[8] McMaster Univ, Firestone Inst Resp Hlth, Dept Med, Hamilton, ON, Canada
[9] Univ Toronto, Sunnybrook Hlth Sci Ctr, Dept Med, Toronto, ON, Canada
[10] Univ Manitoba, Dept Internal Med, Winnipeg, MB, Canada
[11] Univ Manitoba, Dept Physiol, Winnipeg, MB, Canada
[12] Univ Manitoba, Dept Pathophysiol, Winnipeg, MB, Canada
[13] Hosp Sick Children, Child Hlth Evaluat Sci, Toronto, ON, Canada
关键词
economics; hypersensitivity pneumonia; idiopathic pulmonary fibrosis; interstitial lung disease; IDIOPATHIC PULMONARY-FIBROSIS; CROSS-SECTIONAL SURVEY; QUALITY-OF-LIFE; WORK PRODUCTIVITY; ASTHMA CONTROL; COUGH; VALIDITY; BURDEN; STANDARDIZATION; QUESTIONNAIRE;
D O I
10.1016/j.chest.2019.04.016
中图分类号
R4 [临床医学];
学科分类号
1002 ; 100602 ;
摘要
BACKGROUND: Fibrotic interstitial lung diseases (ILDs) are highly morbid chronic disorders that frequently occur in working age individuals. The goal of this study was to determine workplace productivity loss, its determinants, and its estimated costs in patients with fibrotic ILD. METHODS: Patients with idiopathic pulmonary fibrosis, chronic hypersensitivity pneumonitis, idiopathic nonspecific interstitial pneumonia, or unclassifiable ILD were identified from the six-center Canadian Registry for Pulmonary Fibrosis (CARE-PF). The Work Productivity and Activity Impairment questionnaire was used to determine health-related productivity loss. Independent predictors of low workplace productivity were identified by using multivariate regression. Patient data were compared with Canadian population census data. The average productivity loss (hours per week) and the individual's hourly wage were used to estimate the costs of productivity loss. RESULTS: Of 650 eligible patients, 148 (23%) were employed. Productivity loss was reported by 55% of employed patients with an average productivity loss of 7.8 +/- 0.9 h per week (2.3 +/- 0.6 h per week related to absenteeism and 5.5 +/- 0.6 h per week related to presenteeism). Employment among patients with ILD aged 25 to 54 years was 23% lower than the age- and sex-matched general Canadian population (60% vs 83%; P < .001). Employment among patients with ILD aged >= 55 years was 18% lower than in the age- and sex-matched population (20% vs 38%; P < .001). Dyspnea and cough were independent predictors of workplace productivity loss. Estimated annual costs of productivity loss were 11,610 Canadian dollars per employee with ILD. CONCLUSION: Workplace productivity loss is common in fibrotic ILD, strongly correlated with symptom severity, and associated with significant cost.
引用
收藏
页码:887 / 895
页数:9
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