Intoxication With Bourbon Versus Vodka: Effects on Hangover, Sleep, and Next-Day Neurocognitive Performance in Young Adults

被引:71
作者
Rohsenow, Damaris J. [1 ]
Howland, Jonathan [2 ]
Arnedt, J. Todd [3 ]
Almeida, Alissa B. [2 ]
Greece, Jacey [2 ]
Minsky, Sara [2 ]
Kempler, Carrie S. [2 ]
Sales, Suzanne [1 ]
机构
[1] Brown Univ, Ctr Alcohol & Addict Studies, Providence, RI 02912 USA
[2] Boston Univ, Sch Publ Hlth, Youth Alcohol Prevent Ctr, Boston, MA USA
[3] Univ Michigan, Sch Med, Ann Arbor, MI USA
关键词
Hangover; Polysomnography; Neuropsychology; Alcohol Administration; Congeners; Residual Alcohol Effects; ALCOHOL HANGOVER; SIMULATOR PERFORMANCE; AIRCRAFT PILOTS; MENSTRUAL-CYCLE; PSYCHOMOTOR; ETHANOL; DRINKING; MOOD; ELIMINATION; IMPAIRMENT;
D O I
10.1111/j.1530-0277.2009.01116.x
中图分类号
R194 [卫生标准、卫生检查、医药管理];
学科分类号
摘要
Background: This study assessed the effects of heavy drinking with high or low congener beverages on next-day neurocognitive performance, and the extent to which these effects were mediated by alcohol-related sleep disturbance or alcoholic beverage congeners, and correlated with the intensity of hangover. Methods: Healthy heavy drinkers age 21 to 33 (n = 95) participated in 2 drinking nights after an acclimatization night. They drank to a mean of 0.11 g% breath alcohol concentration on vodka or bourbon one night with matched placebo the other night, randomized for type and order. Polysomnography recordings were made overnight; self-report and neurocognitive measures were assessed the next morning. Results: After alcohol, people had more hangover and more decrements in tests requiring both sustained attention and speed. Hangover correlated with poorer performance on these measures. Alcohol decreased sleep efficiency and rapid eye movement sleep, and increased wake time and next-day sleepiness. Alcohol effects on sleep correlated with hangover but did not mediate the effects on performance. No effect of beverage congeners was found except on hangover severity, with people feeling worse after bourbon. Virtually no sex differences appeared. Conclusions: As drinking to this level affects complex cognitive abilities, safety could be affected, with implications for driving and for safety-sensitive occupations. Congener content affects only how people feel the next day so does not increase risk. The sleep disrupting effects of alcohol did not account for the impaired performance so other mechanisms of effect need to be sought. As hangover symptoms correlate with impaired performance, these might be contributing to the impairment.
引用
收藏
页码:509 / 518
页数:10
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