Pigmentary changes in aged and photoaged skin

被引：47
作者：
Castanet, J
Ortonne, JP
机构：
[1] Dermatology Service, Hôpital Archet, Nice
[2] Service de Dermatologie, Hôpital Archet 2, 06202 Nice Cedex 3
来源：
ARCHIVES OF DERMATOLOGY | 1997年 / 133卷 / 10期
关键词：
D O I：
10.1001/archderm.133.10.1296
中图分类号：
R75 [皮肤病学与性病学];
学科分类号：
100206 ;
摘要：
Progress has been made in defining the structural and functional alterations that occur in skin with age. Changes caused solely by longevity have been delineated from changes due to long-term sun exposure, Uneven pigmentation is 1 of the major changes in the gross morphologic characteristics of the aging skin and is much more marked in sun-exposed areas. In the epidermis, melanin pigments are good indicators of photoaging. Ultraviolet radiation plays a major role in the induction of melanocyte aging and may severely damage the melanocyte system of the skin, resulting in both hypermelanotic and hypomelanotic lesions.
引用
收藏
页码：1296 / 1299
页数：4
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