Effects of the Fragrance Galaxolide on the Biomarker Responses of the Clam Ruditapes philippinarum

被引：5

作者：

Rilievo, Graziano ^{[1
]}

Fabrello, Jacopo ^{[1
]}

Roverso, Marco ^{[2
]}

Bogialli, Sara ^{[2
]}

Matozzo, Valerio ^{[1
]}

机构：

[1] Univ Padua, Dept Biol, Via Ugo Bassi 58-B, I-35131 Padua, Italy

[2] Univ Padua, Dept Chem Sci, Via Marzolo 1, I-35131 Padua, Italy

来源：

JOURNAL OF MARINE SCIENCE AND ENGINEERING | 2021年 / 9卷 / 05期

关键词：

fragrance; galaxolide; bivalves; mussels; biomarkers; SYNTHETIC MUSK FRAGRANCES; PERSONAL CARE PRODUCTS; CHROMATOGRAPHY-MASS SPECTROMETRY; ENVIRONMENTAL RISK-ASSESSMENT; ANTIOXIDANT ENZYME-ACTIVITIES; POLYCYCLIC MUSKS; OXIDATIVE STRESS; MYTILUS-GALLOPROVINCIALIS; CHOLINESTERASE ACTIVITY; AQUATIC ORGANISMS;

D O I：

10.3390/jmse9050509

中图分类号：

U6 [水路运输]; P75 [海洋工程];

学科分类号：

0814 ; 081505 ; 0824 ; 082401 ;

摘要：

The musk fragrance Galaxolide(R) (HHCB) is widely used in personal care and household products. Its large use leads to a continuous release of the compound into aquatic environments. Although some studies on the presence of HHCB in ecosystems and biota have been conducted, limited data about its effects on organism biomarkers are available. This study aimed at investigating both cellular and biochemical effects of HHCB in the clam Ruditapes philippinarum. Mussels were exposed for 7, 14 and 21 days to 100 ng/L and 500 ng/L of HHCB in seawater, and the effects on haemocyte parameters and antioxidant enzyme activities in the gills and digestive gland were evaluated. In addition, the neurotoxic potential of HHCB and its capacity to cause oxidative damage to proteins were assessed. Overall, our results demonstrated that exposure to HHCB was able to induce changes in biomarker responses of mussels, mainly at the cellular level.

引用

页数：15

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