Enzyme@silica nanoflower@metal-organic framework hybrids: A novel type of integrated nanobiocatalysts with improved stability

被引：46
作者：
Du, Yingjie [1 ]
Gao, Jing [1 ,2 ]
Liu, Huajiao [1 ]
Zhou, Liya [1 ]
Ma, Li [1 ]
He, Ying [1 ]
Huang, Zhihong [1 ]
Jiang, Yanjun [1 ,2 ]
机构：
[1] Hebei Univ Technol, Sch Chem Engn & Technol, 8 Guangrong Rd, Tianjin 300130, Peoples R China
[2] Hebei Univ Technol, Hebei Prov Key Lab Green Chem Technol & High Effi, 8 Guangrong Rd, Tianjin 300130, Peoples R China
来源：
NANO RESEARCH | 2018年 / 11卷 / 08期
基金：
中国国家自然科学基金;
关键词：
silica nanoflower; metal-organic framework; hybrids; nanobiocatalyst; immobilization; ZEOLITIC IMIDAZOLATE FRAMEWORKS; PENICILLIN-G ACYLASE; CORE-SHELL; COVALENT IMMOBILIZATION; GOLD NANOPARTICLES; FACILE SYNTHESIS; PERFORMANCE; CATALASE; BIOCATALYSTS; CATALYSIS;
D O I：
10.1007/s12274-018-2027-7
中图分类号：
O64 [物理化学（理论化学）、化学物理学];
学科分类号：
070304 ; 081704 ;
摘要：
A novel integrated nanobiocatalyst system based on an enzyme@silica nanoflower@metal-organic framework (enzyme@SNF@ZIF-8) structure with improved stability is fabricated for the first time. The versatility of this system is validated using penicillin G acylase (PGA) and catalase (CAT) as model enzymes. The microporous ZIF-8 layer can be controlled by varying the number of ZIF-8 coating cycles, which produces PGA@SNF@ZIF-8 nanobiocatalysts with different ZIF-8 layer thicknesses. After the second ZIF-8 coating cycle, a PGA@SNF@ZIF-8(2) structure with a homogeneous and well-intergrown ZIF-8 layer is formed, which possesses excellent mechanical and chemical stability. Moreover, PGA@SNF@ZIF-8(2) shows improved thermal/storage stability and reusability compared with free PGA and PGA immobilized on silica nanoflowers (PGA@SNF). The obtained CAT-based nanobiocatalysts (CAT@SNF@ZIF-8(2)) also show excellent catalytic performance.
引用
收藏
页码：4380 / 4389
页数：10
相关论文
共 54 条
[1]   Immobilisation and application of lipases in organic media [J].
Adlercreutz, Patrick .
CHEMICAL SOCIETY REVIEWS, 2013, 42 (15) :6406-6436
[2]   Enzyme nanoarchitectonics: organization and device application [J].
Ariga, Katsuhiko ;
Ji, Qingmin ;
Mori, Taizo ;
Naito, Masanobu ;
Yamauchi, Yusuke ;
Abe, Hideki ;
Hill, Jonathan P. .
CHEMICAL SOCIETY REVIEWS, 2013, 42 (15) :6322-6345
[3]   UiO-66@ SiO2 core-shell microparticles as stationary phases for the separation of small organic molecules [J].
Arrua, R. D. ;
Peristyy, A. ;
Nesterenko, P. N. ;
Das, A. ;
D'Alessandro, D. M. ;
Hilder, E. F. .
ANALYST, 2017, 142 (03) :517-524
[4]  
Avci C., 2015, Angew. Chem., V127, P14625, DOI [10.1002/ange.201507588, DOI 10.1002/ANGE.201507588]
[5]   Structural and functional stabilization of L-asparaginase via multisubunit immobilization onto highly activated supports [J].
Balcao, VM ;
Mateo, C ;
Fernández-Lafuente, R ;
Malcata, FX ;
Guisán, JM .
BIOTECHNOLOGY PROGRESS, 2001, 17 (03) :537-542
[6]   High-throughput synthesis of zeolitic imidazolate frameworks and application to CO2 capture [J].
Banerjee, Rahul ;
Phan, Anh ;
Wang, Bo ;
Knobler, Carolyn ;
Furukawa, Hiroyasu ;
O'Keeffe, Michael ;
Yaghi, Omar M. .
SCIENCE, 2008, 319 (5865) :939-943
[7]   Strategies for the one-step immobilization-purification of enzymes as industrial biocatalysts [J].
Barbosa, Oveimar ;
Ortiz, Claudia ;
Berenguer-Murcia, Angel ;
Torres, Rodrigo ;
Rodrigues, Rafael C. ;
Fernandez-Lafuente, Roberto .
BIOTECHNOLOGY ADVANCES, 2015, 33 (05) :435-456
[8]  
Bayal N., 2016, ANGEW CHEM, V6, P24888, DOI DOI 10.1002/ANGE.201003451
[9]   Effect of pore size on the performance of immobilised enzymes [J].
Bayne, Lauren ;
Ulijn, Rein V. ;
Halling, Peter J. .
CHEMICAL SOCIETY REVIEWS, 2013, 42 (23) :9000-9010
[10]   Design of Surface-Active Artificial Enzyme Particles to Stabilize Pickering Emulsions for High-Performance Biphasic Biocatalysis [J].
Chen, Zhaowei ;
Zhao, Chuanqi ;
Ju, Enguo ;
Ji, Haiwei ;
Ren, Jinsong ;
Binks, Bernard P. ;
Qu, Xiaogang .
ADVANCED MATERIALS, 2016, 28 (08) :1682-1688
123456