A radical based addition-elimination route for the preparation of indoles

被引：28

作者：

Murphy, JA

Scott, KA

Sinclair, RS

Martin, CG

Kennedy, AR

Lewis, N

机构：

[1] Univ Strathclyde, Dept Pure & Appl Chem, Glasgow G1 1XL, Lanark, Scotland

[2] SmithKline Beecham Pharmaceut, Tonbridge TN11 9AN, Kent, England

来源：

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 | 2000年 / 15期

关键词：

D O I：

10.1039/b002565h

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Indoles, including tricyclic derivatives, are produced by cyclisations of aryl radicals onto vinyl halides followed by elimination of halide radical and tautomerism of the resulting product; the aryl radicals are produced using "clean methodology" either by reaction of iodide ions with arenediazonium salts or by reaction of phosphorus-centred radicals with aryl iodides.

引用

收藏

页码：2395 / 2408

页数：14

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