A radical based addition-elimination route for the preparation of indoles

被引：28
作者：
Murphy, JA
Scott, KA
Sinclair, RS
Martin, CG
Kennedy, AR
Lewis, N
机构：
[1] Univ Strathclyde, Dept Pure & Appl Chem, Glasgow G1 1XL, Lanark, Scotland
[2] SmithKline Beecham Pharmaceut, Tonbridge TN11 9AN, Kent, England
来源：
JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 | 2000年 / 15期
关键词：
D O I：
10.1039/b002565h
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Indoles, including tricyclic derivatives, are produced by cyclisations of aryl radicals onto vinyl halides followed by elimination of halide radical and tautomerism of the resulting product; the aryl radicals are produced using "clean methodology" either by reaction of iodide ions with arenediazonium salts or by reaction of phosphorus-centred radicals with aryl iodides.
引用
收藏
页码：2395 / 2408
页数：14
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