ORCA3, a jasmonate-responsive transcriptional regulator of plant primary and secondary metabolism

被引：687

作者：

van der Fits, L ^{[1
]}

Memelink, J ^{[1
]}

机构：

[1] Leiden State Univ, Inst Mol Plant Sci, Clusius Lab, NL-2333 AL Leiden, Netherlands

来源：

SCIENCE | 2000年 / 289卷 / 5477期

关键词：

D O I：

10.1126/science.289.5477.295

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Biosynthesis of many classes of secondary metabolites in plants is induced by the stress hormone jasmonate. The gene for ORCA3, a jasmonate-responsive APETALA2 (AP2)-domain transcription factor from Catharanthus roseus, was isolated by transferred DNA activation tagging. Orca3 overexpression resulted in enhanced expression of several metabolite biosynthetic genes and, consequently, in increased accumulation of terpenoid indole alkaloids, Regulation of metabolite biosynthetic genes by jasmonate-responsive AP2-domain transcription factors may link plant stress responses to changes in metabolism.

引用

页码：295 / 297

页数：3

共 13 条

[1] METHYL JASMONATE VAPOR INCREASES THE DEVELOPMENTALLY CONTROLLED SYNTHESIS OF ALKALOIDS IN CATHARANTHUS AND CINCHONA SEEDLINGS [J].

AERTS, RJ ;

GISI, D ;

DECAROLIS, E ;

DELUCA, V ;

BAUMANN, TW .

PLANT JOURNAL, 1994, 5 (05) :635-643

[2] High level transcription of a member of a repeated gene family confers dehydration tolerance to callus tissue of Craterostigma plantagineum [J].

Furini, A ;

Koncz, C ;

Salamini, F ;

Bartels, D .

EMBO JOURNAL, 1997, 16 (12) :3599-3608

[3] A CHIMERIC TRYPTOPHAN DECARBOXYLASE GENE AS A NOVEL SELECTABLE MARKER IN PLANT-CELLS [J].

GODDIJN, OJM ;

SCHOUTEN, PMV ;

SCHILPEROORT, RA ;

HOGE, JHC .

PLANT MOLECULAR BIOLOGY, 1993, 22 (05) :907-912

[4] CKI1, a histidine kinase homolog implicated in cytokinin signal transduction [J].

Kakimoto, T .

SCIENCE, 1996, 274 (5289) :982-985

[5] ALKALOID BIOSYNTHESIS - THE BASIS FOR METABOLIC ENGINEERING OF MEDICINAL-PLANTS [J].

KUTCHAN, TM .

PLANT CELL, 1995, 7 (07) :1059-1070

[6] A novel jasmonate- and elicitor-responsive element in the periwinkle secondary metabolite biosynthetic gene Str interacts with a jasmonate- and elicitor-inducible AP2-domain transcription factor, ORCA2 [J].

Menke, FLH ;

Champion, A ;

Kijne, JW ;

Memelink, J .

EMBO JOURNAL, 1999, 18 (16) :4455-4463

[7] How genes paint flowers and seeds [J].

Mol, J ;

Grotewold, E ;

Koes, R .

TRENDS IN PLANT SCIENCE, 1998, 3 (06) :212-217

[8] INTERACTION BETWEEN THE TOBACCO DNA-BINDING ACTIVITY CBF AND THE CYT-1 PROMOTER ELEMENT OF THE AGROBACTERIUM-TUMEFACIENS T-DNA GENE T-CYT CORRELATES WITH CYT-1 DIRECTED GENE-EXPRESSION IN MULTIPLE TOBACCO TISSUE TYPES [J].

NEUTEBOOM, STC ;

STOFFELS, A ;

HULLEMAN, E ;

MEMELINK, J ;

SCHILPEROORT, RA ;

HOGE, JHC .

PLANT JOURNAL, 1993, 4 (03) :525-534

[9]

Riechmann JL, 1998, BIOL CHEM, V379, P633

[10] Multicellular compartmentation of Catharanthus roseus alkaloid biosynthesis predicts intercellular translocation of a pathway intermediate [J].

St-Pierre, B ;

Vazquez-Flota, FA ;

De Luca, V .

PLANT CELL, 1999, 11 (05) :887-900

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