Pancreatic Manifestations of von Hippel-Lindau Disease

被引：0

作者：

Safo, Anthony-Osei F. ^{[1
]}

Pambuccian, Stefan E. ^{[1
]}

机构：

[1] Univ Minnesota, Med Ctr Fairview, Dept Lab Med & Pathol, Minneapolis, MN 55455 USA

来源：

ARCHIVES OF PATHOLOGY & LABORATORY MEDICINE | 2010年 / 134卷 / 07期

关键词：

SOLID-PSEUDOPAPILLARY TUMOR; RENAL-CELL CARCINOMA; NEUROENDOCRINE TUMORS; SUPPRESSOR GENE; LESIONS; PRODUCT;

D O I：

暂无

中图分类号：

R446 [实验室诊断]; R-33 [实验医学、医学实验];

学科分类号：

1001 ;

摘要：

Von Hippel-Lindau disease is an uncommon, multisystem, multitumor disorder that can present in sporadic form but is more commonly inherited as an autosomal-dominant disease with high penetrance. Affected patients are at increased risk for developing multiple synchronous or metachronous benign or malignant, cystic, and vascular neoplasms of various organs. The characteristic neoplasms associated with von Hippel-Lindau are hemangioblastoma of the central nervous system and retina, clear cell renal cell carcinoma, and pheochromocytoma, but other lesions are well recognized. Pancreatic lesions, both primary and metastatic, are common, and several differential diagnostic possibilities must be considered. (Arch Pathol Lab Med. 2010;134:1080-1083)

引用

页码：1080 / 1083

页数：4