Primary angiosarcoma of the prostate: a case report and literature review

Primary sarcomas of the prostate are rare, accounting for about 0.1% of all prostatic malignancies. Prostate angiosarcoma is exceedingly rare with only sixteen cases reported in the literature to date. Seven out of the sixteen cases were followed by radiotherapy for prostate adenocarcinoma. Despite the rarity, it usually presents with no detectable serum prostate-specific antigen levels and poor prognosis, representing a diagnosis and treatment challenge. The present study reports a new case of primary prostate angiosarcoma without radiation exposure history, reviewing the clinical symptoms, morphologic changes, prognosis, and treatment of angiosarcomas of the prostate.