Lymphocytes Subsets Reference Values in Childhood

被引：98

作者：

Tosato, F. ^{[1
]}

Bucciol, G. ^{[2
]}

Pantano, G. ^{[1
]}

Putti, M. C. ^{[2
]}

Sanzari, M. C. ^{[1
]}

Basso, G. ^{[2
]}

Plebani, M. ^{[1
]}

机构：

[1] Univ Hosp Padova, Dept Lab Med, I-35128 Padua, Italy

[2] Univ Hosp Padova, Dept Pediat Hematol Oncol, I-35128 Padua, Italy

来源：

CYTOMETRY PART A | 2015年 / 87A卷 / 01期

关键词：

lymphocyte subsets; reference values; pediatric population; primary immunodeficiencies; AGE-RELATED-CHANGES; HEALTHY-CHILDREN; PERIPHERAL-BLOOD; NORMAL RANGES; SUBPOPULATIONS; INFANTS; BIRTH; SEX;

D O I：

10.1002/cyto.a.22520

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Immunophenotyping of blood lymphocyte subsets and activation markers is a basic tool in the diagnostic process of primary immunodeficiency diseases, its use becoming more and more widespread as the knowledge about these illnesses increases. However, the availability of reliable reference values, which need to be age-matched for the pediatric population, is a pre-requisite for the reliable interpretation of immunophenotyping data. Aim of this study is to analyze the lymphocyte subsets and activation markers distribution in children aged 0-18 years referring to the University Hospital of Padova and to create age-matched reference values expressed by percentiles, thus providing a valuable guideline for the interpretation of the immunophenotype. (c) 2014 International Society for Advancement of Cytometry

引用

页码：81 / 85

页数：5

共 31 条

[1]

[Anonymous], 2008, DEFINING ESTABLISHIN, DOI DOI 10.1515/CCLM-2013-0249

[2]

[Anonymous], 2007, H42A2 CLSI

[3]

BABCOCK GF, 1987, DIAGN CLIN IMMUNOL, V5, P175

[4] COMPARISON OF CORD-BLOOD AND ADULT-BLOOD LYMPHOCYTE NORMAL RANGES - A POSSIBLE EXPLANATION FOR DECREASED SEVERITY OF GRAFT-VERSUS-HOST DISEASE AFTER CORD-BLOOD TRANSPLANTATION [J].