Management of Locally Advanced Esophageal Cancer

被引:3
作者
Thakur, Binay [1 ]
Devkota, Mukti [1 ]
Chaudhary, Manish [1 ]
机构
[1] BP Koirala Mem Canc Hosp, Dept Surg Oncol, Bharatpur, Nepal
关键词
combined modality therapy; esophageal cancer; esophagectomy; SQUAMOUS-CELL CARCINOMA; PHASE-III TRIAL; CHEMORADIOTHERAPY PLUS SURGERY; DEFINITIVE CHEMORADIOTHERAPY; RADICAL SURGERY; PREOPERATIVE CHEMORADIOTHERAPY; PERIOPERATIVE CHEMOTHERAPY; SALVAGE ESOPHAGECTOMY; RADIOTHERAPY; CHEMORADIATION;
D O I
10.31729/jnma.4299
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
Esophageal cancer is diagnosed usually at a locally advanced stage. Surgery alone has less optimal results and a multimodality approach has been established as the standard of care for cII-III stages of esophageal cancer. This review focuses on the recent evidences of management of esophageal cancer with various variations in approaches in Eastern and Western countries. The major difference is the selection of induction treatment. Till the results of some ongoing trials become available, most of the evidences support neoadjuvant chemoradiation followed by surgery for squamous cell carcinoma and perioperative chemotherapy and surgery for adenocarcinoma.
引用
收藏
页码:409 / 416
页数:8
相关论文
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[1]   Perioperative chemotherapy with fluorouracil plus leucovorin, oxaliplatin, and docetaxel versus fluorouracil or capecitabine plus cisplatin and epirubicin for locally advanced, resectable gastric or gastro-oesophageal junction adenocarcinoma (FLOT4): a randomised, phase 2/3 trial [J].
Al-Batran, Salah-Eddin ;
Homann, Nils ;
Pauligk, Claudia ;
Goetze, Thorsten O. ;
Meiler, Johannes ;
Kasper, Stefan ;
Kopp, Hans-Georg ;
Mayer, Frank ;
Haag, Georg Martin ;
Luley, Kim ;
Lindig, Udo ;
Schmiegel, Wolff ;
Pohl, Michael ;
Stoehlmacher, Jan ;
Folprecht, Gunnar ;
Probst, Stephan ;
Prasnikar, Nicole ;
Fischbach, Wolfgang ;
Mahlberg, Rolf ;
Trojan, Joerg ;
Koenigsmann, Michael ;
Martens, Uwe M. ;
Thuss-Patience, Peter ;
Egger, Matthias ;
Block, Andreas ;
Heinemann, Volker ;
Illerhaus, Gerald ;
Moehler, Markus ;
Schenk, Michael ;
Kullmann, Frank ;
Behringer, Dirk M. ;
Heike, Michael ;
Pink, Daniel ;
Teschendorf, Christian ;
Loehr, Carmen ;
Bernhard, Helga ;
Schuch, Gunter ;
Rethwisch, Volker ;
von Weikersthal, Ludwig Fischer ;
Hartmann, Joerg T. ;
Kneba, Michael ;
Daum, Severin ;
Schulmann, Karsten ;
Weniger, Joerg ;
Belle, Sebastian ;
Gaiser, Timo ;
Oduncu, Fuat S. ;
Guentner, Martina ;
Hozaeel, Wael ;
Reichart, Alexander .
LANCET, 2019, 393 (10184) :1948-1957
[2]  
An Feng-shan, 2003, Zhonghua Zhongliu Zazhi, V25, P376
[3]   Surgery plus chemotherapy compared with surgery alone for localized squamous cell carcinoma of the thoracic esophagus: A Japan Clinical Oncology Group Study - JCOG9204 [J].
Ando, N ;
Iizuka, T ;
Ide, H ;
Ishida, K ;
Shinoda, M ;
Nishimaki, T ;
Takiyama, W ;
Watanabe, H ;
Isono, K ;
Aoyama, N ;
Makuuchi, H ;
Tanaka, O ;
Yamana, H ;
Ikeuchi, S ;
Kabuto, T ;
Nagai, K ;
Shimoda, Y ;
Kinjo, Y .
JOURNAL OF CLINICAL ONCOLOGY, 2003, 21 (24) :4592-4596
[4]   A Randomized Trial Comparing Postoperative Adjuvant Chemotherapy with Cisplatin and 5-Fluorouracil Versus Preoperative Chemotherapy for Localized Advanced Squamous Cell Carcinoma of the Thoracic Esophagus (JCOG9907) [J].
Ando, Nobutoshi ;
Kato, Hoichi ;
Igaki, Hiroyasu ;
Shinoda, Masayuki ;
Ozawa, Soji ;
Shimizu, Hideaki ;
Nakamura, Tsutomu ;
Yabusaki, Hiroshi ;
Aoyama, Norio ;
Kurita, Akira ;
Ikeda, Kenichiro ;
Kanda, Tatsuo ;
Tsujinaka, Toshimasa ;
Nakamura, Kenichi ;
Fukuda, Haruhiko .
ANNALS OF SURGICAL ONCOLOGY, 2012, 19 (01) :68-74
[5]   PROSPECTIVE COMPARISON OF SURGERY ALONE AND CHEMORADIOTHERAPY WITH SELECTIVE SURGERY IN RESECTABLE SQUAMOUS CELL CARCINOMA OF THE ESOPHAGUS [J].
Ariga, Hisanori ;
Nemoto, Kenji ;
Miyazaki, Shukichi ;
Yoshioka, Takashi ;
Ogawa, Yohishiro ;
Sakayauchi, Toru ;
Jingu, Keiichi ;
Miyata, Go ;
Onodera, Ko ;
Ichikawa, Hirofumi ;
Kamei, Takashi ;
Kato, Shunsuke ;
Ishioka, Chikashi ;
Satomi, Susumu ;
Yamada, Shogo .
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2009, 75 (02) :348-356
[6]   LOW-DOSE PREOPERATIVE RADIOTHERAPY FOR CARCINOMA OF THE ESOPHAGUS - RESULTS OF A RANDOMIZED CLINICAL-TRIAL [J].
ARNOTT, SJ ;
DUNCAN, W ;
KERR, GR ;
WALBAUM, PR ;
CAMERON, E ;
JACK, WJL ;
MACKILLOP, WJ .
RADIOTHERAPY AND ONCOLOGY, 1992, 24 (02) :108-113
[7]  
Bedenne L, 2007, J CLIN ONCOL, V25, P1160, DOI 10.1200/JCO.2005.04.7118
[8]   Is concurrent radiation therapy required in patients receiving preoperative chemotherapy for adenocarcinoma of the oesophagus? A randomised phase II trial [J].
Burmeister, Bryan H. ;
Thomas, Janine M. ;
Burmeister, Elizabeth A. ;
Walpole, Euan T. ;
Harvey, Jennifer A. ;
Thomson, Damien B. ;
Barbour, Andrew P. ;
Gotley, David C. ;
Smithers, B. Mark .
EUROPEAN JOURNAL OF CANCER, 2011, 47 (03) :354-360
[9]   Effects of neoadjuvant radiochemotherapy on pathological staging and prognosis for locally advanced esophageal squamous cell carcinoma [J].
Cao, X. -F. ;
He, X. -T. ;
Ji, L. ;
Xiao, J. ;
Lv, J. .
DISEASES OF THE ESOPHAGUS, 2009, 22 (06) :477-481
[10]   Perioperative chemotherapy versus surgery alone for resectable gastroesophageal cancer [J].
Cunningham, David ;
Allum, William H. ;
Stenning, Sally P. ;
Thompson, Jeremy N. ;
Van de Velde, Cornelis J. H. ;
Nicolson, Marianne ;
Scarffe, J. Howard ;
Lofts, Fiona J. ;
Falk, Stephen J. ;
Iveson, Timothy J. ;
Smith, David B. ;
Langley, Ruth E. ;
Verma, Monica ;
Weeden, Simon ;
Chua, Yu Jo .
NEW ENGLAND JOURNAL OF MEDICINE, 2006, 355 (01) :11-20