Unusual 2(1H)-Pyrazinones Isolated from a Culture of a Brazilian Marine-Derived Streptomyces sp.

被引：0

作者：

Thomasi, Sergio S. ^{[1
]}

Granato, Ana C. ^{[2
]}

Romano, Luis H. ^{[3
]}

Dhooghe, Liene ^{[4
]}

do Nascimento, Eduardo S. P. ^{[1
]}

Badino, Alberto C. ^{[3
]}

da Silva, Maria F. G. F. ^{[1
]}

Ferreira, Antonio G. ^{[1
]}

Venancio, Tiago ^{[1
]}

机构：

[1] Univ Fed Sao Carlos, Dept Quim, BR-13565905 Sao Carlos, SP, Brazil

[2] Univ Fed Triangulo Mineiro, Dept Engn Quim, BR-38025180 Uberaba, MG, Brazil

[3] Univ Fed Sao Carlos, Dept Engn Quim, BR-13565905 Sao Carlos, SP, Brazil

[4] Univ Antwerp, B-2020 Antwerp, Belgium

来源：

NATURAL PRODUCT COMMUNICATIONS | 2014年 / 9卷 / 09期

基金：

巴西圣保罗研究基金会;

关键词：

LC-SPE/NMR; Marine; Streptomyces; Secondary metabolite; 2(1H)-Pyrazinones; NATURAL-PRODUCTS; METABOLITES; ARGLECIN;

D O I：

暂无

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Four new secondary metabolites, giovaninones A-D (1-4), were isolated from an ethyl acetate extract of a culture of a marine-derived Streptomyces strain designated SS99BA-2. Chemical analysis was completely conducted in a coupled automated LC-SPE system with the use of a cryogenic NMR probehead and FIRMS. The application of this system to identify, purify and elucidate all the structures is described.

引用

页码：1275 / 1278

页数：4

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