Carbohydrate-Catalyzed Enantioselective Alkene Diboration: Enhanced Reactivity of 1,2-Bonded Diboron Complexes

被引：93

作者：

Fang, Lichao ^{[1
]}

Yan, Lu ^{[1
]}

Haeffner, Fredrik ^{[1
]}

Morken, James P. ^{[1
]}

机构：

[1] Boston Coll, Merkert Chem Ctr, Dept Chem, Chestnut Hill, MA 02467 USA

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2016年 / 138卷 / 08期

关键词：

N-HETEROCYCLIC CARBENES; ASYMMETRIC-SYNTHESIS; CONJUGATE ADDITIONS; CHIRAL DIOLS; ESTERS; KETONES; ENONES; ALDEHYDES;

D O I：

10.1021/jacs.5b13174

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Catalytic enantioselective diboration of alkenes is accomplished with readily available carbohydrate-derived catalysts. Mechanistic experiments suggest the intermediacy of 1,2-bonded diboronates.

引用

页码：2508 / 2511

页数：4

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