Risk of cancer in patients with biopsy-proven giant cell arteritis

被引：21

作者：

Hill, Catherine L. ^{[1
]}

Cole, Antonia ^{[1
]}

Rischmueller, Maureen ^{[1
]}

Dodd, Thomas ^{[2
]}

Coleman, Mark ^{[3
]}

Tucker, Graeme ^{[4
]}

Roberts-Thomson, Peter ^{[5
]}

机构：

[1] Queen Elizabeth Hosp, Rheumatol Unit, Woodville, SA 5011, Australia

[2] SA Pathol, Dept Tissue Pathol, Adelaide, SA, Australia

[3] Flinders Med Ctr, Dept Anat Pathol, Bedford Pk, SA, Australia

[4] Dept Hlth, Hlth Stat Unit, Adelaide, SA, Australia

[5] Flinders Med Ctr, Dept Allergy Immunol & Arthritis, Bedford, SA, Australia

来源：

RHEUMATOLOGY | 2010年 / 49卷 / 04期

关键词：

Giant cell arteritis; Malignancy; Epidemiology; Population;

D O I：

10.1093/rheumatology/kep409

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Objective. Results of previous studies investigating the association between GCA and malignancy are conflicting. We performed a study of the risk of cancer in patients with biopsy-proven GCA. Methods. Patients with biopsy-proven GCA were identified from pathology reports of temporal artery biopsies from the major pathology laboratories in South Australia (SA). All subjects with biopsy-proven GCA were linked to the SA Cancer Registry to identify cases of cancer until 31 December 2006. Standardized incidence ratios (SIRs) for cancer were determined using the age-and gender-specific rates for SA. Results. There were 226 cases of biopsy-proven GCA (163 females and 63 males). Thirty-one cases were diagnosed with cancer, following the diagnosis of biopsy-proven GCA. There was no increased risk of cancer among those with biopsy-proven GCA, following the diagnosis of GCA compared with the general population (SIR 1.2; 95% Cl 0.8, 1.6). Conclusion. This cohort study did not demonstrate any increased risk for malignancy in subjects with biopsy-proven GCA.

引用

页码：756 / 759

页数：4

共 6 条

[1] THE SOUTH-AUSTRALIAN-CANCER-REGISTRY - A MEANS OF ASSESSING CANCER INCIDENCE, MORTALITY AND CASE SURVIVAL [J].

BONETT, A ;

RODER, D ;

MILLIKEN, L .

EUROPEAN JOURNAL OF CANCER, 1992, 28A (11) :1923-1926

[2] Cancer in biopsy-proven giant cell arteritis.: A population-based study [J].

Gonzalez-Gay, Miguel A. ;

Lopez-Diaz, Maria J. ;

Martinez-Lado, Luciana ;

Pena-Sagredo, Jose L. ;

Lopez-Agreda, Hugo ;

Miranda-Filloy, Jose A. ;

Gonzalez-Juanatey, Carlos ;

Sanchez-Andrade, Arnalia ;

Martin, Javier ;

Llorca, Javier .

SEMINARS IN ARTHRITIS AND RHEUMATISM, 2007, 37 (03) :156-163

[3]

HAGA HJ, 1993, J RHEUMATOL, V20, P1335

[4] Predictors of colorectal cancer screening participation in the United States [J].

Ioannou, GN ;

Chapko, MK ;

Dominitz, JA .

AMERICAN JOURNAL OF GASTROENTEROLOGY, 2003, 98 (09) :2082-2091

[5]

Liozon E, 2006, J RHEUMATOL, V33, P1606

[6]

Myklebust G, 2002, J RHEUMATOL, V29, P2143

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