A one-pot synthesis of trichloromethylated pyrimidines from trichloroacetimidamides and acetylenic esters

被引：9

作者：

Yavari, Issa ^{[1
]}

Malekafzali, Alaleh ^{[1
]}

Eivazzadeh-Keihan, Reza ^{[1
]}

Skoulika, Stavroula ^{[2
]}

Alivaisi, Rahman ^{[3
]}

机构：

[1] Tarbiat Modares Univ, Dept Chem, POB 14115-175, Tehran, Iran

[2] Univ Ioannina, Dept Chem, Phys Chem Lab, GR-45110 Ioannina, Greece

[3] Islamic Azad Univ, Sci & Res Branch, Dept Chem, Tehran, Iran

来源：

TETRAHEDRON LETTERS | 2016年 / 57卷 / 16期

关键词：

Pyrimidine; Trichloroacetonitrile; Tetramethylguanidine; Acetylenic ester; ISOCYANIDES; FLUORINE;

D O I：

10.1016/j.tetlet.2015.12.066

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A one-pot synthesis of functionalized trichloromethylated pyrimidines from the reaction of trichloroacetimidamides, generated by the addition of guanidine derivatives to trichloroacetonitrile, and acetylenic esters, in good yields is described. (C) 2016 Published by Elsevier Ltd.

引用

页码：1733 / 1735

页数：3

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