Should Early Prone Positioning Be a Standard of Care in ARDS With Refractory Hypoxemia?

被引:10
作者
Marini, John J. [1 ,2 ]
Josephs, Sean A. [3 ]
Mechlin, Maggie [3 ]
Hurford, William E. [3 ]
机构
[1] Univ Minnesota, Minneapolis, MN USA
[2] Reg Hosp, Pulm & Crit Care Dept, St Paul, MN USA
[3] Univ Cincinnati, Dept Anesthesiol, Cincinnati, OH USA
关键词
prone position; refractory hypoxemia; ARDS; mechanical ventilation; respiratory failure; secretion clearance; RESPIRATORY-DISTRESS-SYNDROME; END-EXPIRATORY PRESSURE; ACUTE LUNG INJURY; TIDAL VOLUME VENTILATION; PROTECTIVE-VENTILATION; IMPROVES OXYGENATION; MORTALITY; MECHANISM; FAILURE; TRIAL;
D O I
10.4187/respcare.04562
中图分类号
R4 [临床医学];
学科分类号
1002 ; 100602 ;
摘要
For the past 4 decades, the prone position has been employed as an occasional rescue option for patients with severe hypoxemia unresponsive to conventional measures applied in the supine orientation. Proning offers a high likelihood of significantly improved arterial oxygenation to well selected patients, but until the results of a convincing randomized trial were published, its potential to reduce mortality risk remained in serious doubt. Proning does not benefit patients of all disease severities and stages but may be life-saving for others. Because it requires advanced nursing skills and escalation of monitoring surveillance to deploy safely, its place as an early stage standard of care depends on the definition of that label. (C) 2016 Daedalus Enterprises
引用
收藏
页码:818 / 826
页数:9
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