The Bacillus subtilis acyl lipid desaturase is a Δ5 desaturase

被引：66
作者：
Altabe, SG
Aguilar, P
Caballero, GM
de Mendoza, D
机构：
[1] Univ Nacl Rosario, IBR, Rosario, Argentina
[2] Univ Nacl Rosario, Dept Microbiol, Fac Ciencias Bioquim & Farmaceut, Rosario, Argentina
[3] Secretaria Turismo & Deporte, Lab Control Doping, RA-1429 Buenos Aires, DF, Argentina
来源：
JOURNAL OF BACTERIOLOGY | 2003年 / 185卷 / 10期
关键词：
D O I：
10.1128/JB.185.10.3228-3231.2003
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
Bacillus subtilis was recently reported to synthesize unsaturated fatty acids (UFAs) with a double bond at positions, Delta5, Delta7, and Delta9 (M. H. Weber, W. Klein, L. Muller, U. M. Niess, and M. A. Marahiel, Mol. Microbiol. 39:1321-1329, 2001). Since this finding would have considerable importance in the double-bond positional specificity displayed by the B. subtilis acyl lipid desaturase, we have attempted to confirm this observation. We report that the double bond of UFAs synthesized by B. subtilis is located exclusively at the Delta5 position, regardless of the growth temperature and the length chain of the fatty acids.
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页码：3228 / 3231
页数：4
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