Application of Advanced Nanomaterials for Kidney Failure Treatment and Regeneration

被引：36

作者：

Eftekhari, Aziz ^{[1
,2
]}

Dizaj, Solmaz Maleki ^{[3
]}

Ahmadian, Elham ^{[4
]}

Przekora, Agata ^{[5
]}

Khatibi, Seyed Mahdi Hosseiniyan ^{[4
]}

Ardalan, Mohammadreza ^{[4
]}

Vahed, Sepideh Zununi ^{[4
]}

Valiyeva, Mahbuba ^{[6
]}

Mehraliyeva, Sevil ^{[6
]}

Khalilov, Rovshan ^{[2
,7
,8
]}

Hasanzadeh, Mohammad ^{[9
]}

机构：

[1] Maragheh Univ Med Sci, Pharmacol & Toxicol Dept, Maragheh 7815155158, Iran

[2] Moscow State Pedag Univ, Russian Inst Adv Study, 1-1 Malaya Pirogovskaya St, Moscow 119991, Russia

[3] Tabriz Univ Med Sci, Dent & Periodontal Res Ctr, Tabriz 5166614756, Iran

[4] Tabriz Univ Med Sci, Kidney Res Ctr, Tabriz 5166614756, Iran

[5] Med Univ Lublin, Chair & Dept Biochem & Biotechnol, Chodzki 1 St, PL-20093 Lublin, Poland

[6] Azerbaijan Med Univ, Dept Pharmaceut Technol & Management, AZ-1022 Baku, Azerbaijan

[7] Baku State Univ, Dept Biophys & Biochem, AZ-1148 Baku, Azerbaijan

[8] Azerbaijan Natl Acad Sci, Inst Radiat Problems, AZ-1001 Baku, Azerbaijan

[9] Tabriz Univ Med Sci, Pharmaceut Anal Res Ctr, Tabriz 5166614756, Iran

来源：

MATERIALS | 2021年 / 14卷 / 11期

关键词：

kidney regeneration; therapeutic nanomedicine; exosomes; nanovesicles; carbon nanotubes; nanofibers; electrospinning; synthetic kidney; GLOMERULAR-BASEMENT-MEMBRANE; MULTIWALLED CARBON NANOTUBES; EXTRACELLULAR VESICLES; GROWTH-FACTOR; CONTROLLED-RELEASE; OXIDATIVE STRESS; MESANGIAL CELLS; DRUG-DELIVERY; STEM-CELLS; IN-VIVO;

D O I：

10.3390/ma14112939

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

The implementation of nanomedicine not only provides enhanced drug solubility and reduced off-target adverse effects, but also offers novel theranostic approaches in clinical practice. The increasing number of studies on the application of nanomaterials in kidney therapies has provided hope in a more efficient strategy for the treatment of renal diseases. The combination of biotechnology, material science and nanotechnology has rapidly gained momentum in the realm of therapeutic medicine. The establishment of the bedrock of this emerging field has been initiated and an exponential progress is observed which might significantly improve the quality of human life. In this context, several approaches based on nanomaterials have been applied in the treatment and regeneration of renal tissue. The presented review article in detail describes novel strategies for renal failure treatment with the use of various nanomaterials (including carbon nanotubes, nanofibrous membranes), mesenchymal stem cells-derived nanovesicles, and nanomaterial-based adsorbents and membranes that are used in wearable blood purification systems and synthetic kidneys.

引用

页数：19

共 130 条

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