Effect of radio-frequency electromagnetic radiations (RF-EMR) on passive avoidance behaviour and hippocampal morphology in Wistar rats

被引：66
作者：
Narayanan, Sareesh Naduvil [1 ]
Kumar, Raju Suresh [1 ]
Potu, Bhagath Kumar [2 ]
Nayak, Satheesha [3 ]
Bhat, P. Gopalakrishna [4 ]
Mailankot, Maneesh [5 ]
机构：
[1] Manipal Univ, Melaka Manipal Med Coll, Dept Physiol, Manipal 576104, Karnataka, India
[2] Manipal Univ, Kasturba Med Coll, Dept Anat, Manipal 576104, Karnataka, India
[3] Manipal Univ, Melaka Manipal Med Coll, Dept Anat, Manipal 576104, Karnataka, India
[4] Manipal Univ, Kasturba Med Coll, Dept Biochem, Manipal 576104, Karnataka, India
[5] Manipal Univ, Melaka Manipal Med Coll, Dept Biochem, Manipal 576104, Karnataka, India
来源：
UPSALA JOURNAL OF MEDICAL SCIENCES | 2010年 / 115卷 / 02期
关键词：
OXIDATIVE STRESS; MOBILE PHONES; BRAIN; EXPOSURE; MEMORY; CHOLINE; GLIA; APOPTOSIS; NEURONS; LESIONS;
D O I：
10.3109/03009730903552661
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Introduction. The interaction of mobile phone radio-frequency electromagnetic radiation (RF-EMR) with the brain is a serious concern of our society. Objective. We evaluated the effect of RF-EMR from mobile phones on passive avoidance behaviour and hippocampal morphology in rats. Materials and methods. Healthy male albino Wistar rats were exposed to RF-EMR by giving 50 missed calls (within 1 hour) per day for 4 weeks, keeping a GSM (0.9 GHz/1.8 GHz) mobile phone in vibratory mode (no ring tone) in the cage. After the experimental period, passive avoidance behaviour and hippocampal morphology were studied. Results. Passive avoidance behaviour was significantly affected in mobile phone RF-EMR-exposed rats demonstrated as shorter entrance latency to the dark compartment when compared to the control rats. Marked morphological changes were also observed in the CA(3) region of the hippocampus of the mobile phone-exposed rats in comparison to the control rats. Conclusion. Mobile phone RF-EMR exposure significantly altered the passive avoidance behaviour and hippocampal morphology in rats.
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收藏
页码：91 / 96
页数：6
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