Reduction of cholera in Bangladeshi villages by simple filtration

被引：230

作者：

Colwell, RR

Huq, A

Islam, MS

Aziz, KMA

Yunus, M

Khan, NH

Mahmud, A

Sack, RB

Nair, GB

Chakraborty, J

Sack, DA

Russek-Cohen, E

机构：

[1] Univ Maryland, Inst Biotechnol, Ctr Marine Biotechnol, Baltimore, MD 21202 USA

[2] Univ Maryland, Dept Cell Biol & Mol Genet, College Pk, MD 20742 USA

[3] Int Ctr Diarrhoeal Dis Res, Dhaka 1000, Bangladesh

[4] Johns Hopkins Bloomberg Sch Publ Hlth, Dept Int Hlth, Baltimore, MD 21205 USA

[5] Univ Maryland, Dept Anim & Avian Sci, Biometr Program, College Pk, MD 20742 USA

来源：

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA | 2003年 / 100卷 / 03期

关键词：

D O I：

10.1073/pnas.0237386100

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Based on results of ecological studies demonstrating that Vibrio cholerae, the etiological agent of epidemic cholera, is commensal to zooplankton, notably copepods, a simple filtration procedure was developed whereby zooplankton, most phytoplankton, and particulates >20 mum were removed from water before use. Effective deployment of this filtration procedure, from September 1999 through July 2002 in 65 villages of rural Bangladesh, of which the total population for the entire study comprised approximate to133,000 individuals, yielded a 48% reduction in cholera (P < 0.005) compared with the control.

引用

页码：1051 / 1055

页数：5

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