Isolation and identification of arabinose mycolates of Cell Wall Skeleton (CWS) derived from Mycobacterium bovis BCG Tokyo 172 (SMP-105)

被引：6

作者：

Uenishi, Yuko ^{[1
]}

Kusunose, Naoto ^{[2
]}

Yano, Ikuya ^{[3
]}

Sunagawa, Makoto ^{[4
]}

机构：

[1] Dainippon Sumitomo Pharma Co Ltd, Technol Res & Dev Div, Konohana Ku, Osaka 5540022, Japan

[2] Dainippon Sumitomo Pharma Co Ltd, Drug Res Div, Konohana Ku, Osaka 5540022, Japan

[3] Japan BCG Lab, Kiyose, Tokyo 2040022, Japan

[4] MBR Co Ltd, Toyonaka, Osaka 5608552, Japan

来源：

JOURNAL OF MICROBIOLOGICAL METHODS | 2010年 / 80卷 / 03期

关键词：

Arabinose mycolates; BCG-CWS; SMP-105; Mycobacterium bovis BCG Tokyo 172; COMPONENTS;

D O I：

10.1016/j.mimet.2010.01.003

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

A unique hydrolysis method using a two-layer solution, consisting of diluted hydrochloric acid and toluene was developed to isolate whole arabinose mycolates from the cell wall skeleton of Mycobacterium bovis BCG Tokyo 172 (SMP-105) in order to reveal its pivotal role in enhancing immune responses against tumors. (C) 2010 Elsevier B.V. All rights reserved.

引用

页码：302 / 305

页数：4

共 6 条

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