Green synthesis of benzimidazole derivatives catalyzed by ionic liquid under microwave irradiation

被引:11
|
作者
Qin, Mingcong [1 ,2 ]
Fu, Yujie [1 ,2 ]
Wang, Xiqing [1 ,2 ]
Zhang, Yuhang [1 ,2 ]
Ma, Weidong [1 ,2 ]
机构
[1] Northeast Forestry Univ, State Engn Lab Bioresource Ecoutilizat, Harbin 150040, Peoples R China
[2] Northeast Forestry Univ, Engn Res Ctr Forest Biopreparat, Minist Educ, Harbin 150040, Peoples R China
关键词
Benzimidazole derivatives; Ionic liquid; Microwave irradiation; Response surface methodology; EFFICIENT SYNTHESIS; ORGANIC-SYNTHESIS; PROTOCOL; SYSTEM;
D O I
10.1007/s13738-014-0426-6
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
An efficient synthesis of benzimidazole derivatives from o-phenylene diamine and substituted aromatic aldehyde catalyzed by ionic liquid under microwave irradiation was reported. The synthesis conditions were first optimized by single factor experiments. Then, a central composite design combined with response surface methodology was used to study the most effective factors. Optimal conditions were synthesis time 1 h, the reactant/catalyst molar ratio 1:1:0.200, the temperature 50 A degrees C and the microwave power 500 W. Under optimized conditions, the yields of benzimidazole derivatives were 78.55-97.66 %. This method offered the outstanding advantages, such as faster reaction rate, higher yields, recyclable catalyst, environmental friendliness, and simple workup procedure.
引用
收藏
页码:1553 / 1559
页数:7
相关论文
共 50 条
  • [41] Production of 5-Hydroxymethylfurfural from Cellulose Catalyzed by Lewis Acid under Microwave Irradiation in Ionic Liquid
    Wu Shuchang
    Wang Chunlei
    Gao Yongjun
    Zhang Shaochun
    Ma Ding
    Zhao Zongbao
    CHINESE JOURNAL OF CATALYSIS, 2010, 31 (09) : 1157 - 1161
  • [42] An environmentally benign, green, and efficient ionic liquid catalyzed synthesis of Quinoline derivatives via Knoevenagel condensation
    Tasqeeruddin, Syed
    Asiri, Yahya, I
    JOURNAL OF HETEROCYCLIC CHEMISTRY, 2020, 57 (01) : 132 - 139
  • [43] Synthesis of symmetric triarylmethane derivatives catalyzed by AIL ionic liquid
    Kang, Li Q.
    Gao, Han
    Cai, Yue Q.
    MONATSHEFTE FUR CHEMIE, 2018, 149 (01): : 57 - 62
  • [44] Synthesis of symmetric triarylmethane derivatives catalyzed by AIL ionic liquid
    Li Q. Kang
    Han Gao
    Yue Q. Cai
    Monatshefte für Chemie - Chemical Monthly, 2018, 149 : 57 - 62
  • [45] Lipase catalyzed ascorbyl palmitate synthesis under microwave irradiation
    Costa, Ingrid C. R.
    Sutili, Felipe K.
    da Silva, Gabriela V. V.
    Leite, Selma G. F.
    Miranda, Leandro S. M.
    de Souza, Rodrigo O. M. A.
    JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC, 2014, 102 : 127 - 131
  • [46] Solvent-free liquid-phase synthesis of polyhydroquinoline derivatives under microwave irradiation
    Zhang, Xiao-Lan
    Sheng, Shou-Ri
    Liu, Xian-Liang
    Liu, Xiao-Ling
    ARKIVOC, 2007, : 79 - 86
  • [47] Effect of ionic liquid properties on lipase stabilization under microwave irradiation
    Zhao, Hua
    Baker, Gary A.
    Song, Zhiyan
    Olubajo, Olarongbe
    Zanders, Lavezza
    Campbell, Sophia M.
    JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC, 2009, 57 (1-4) : 149 - 157
  • [48] Ionic liquid promoted selective debromination of α-bromoketones under microwave irradiation
    Ranu, Brindaban C.
    Chattopadhyay, Kalicharan
    Jana, Ranjan
    TETRAHEDRON, 2007, 63 (01) : 155 - 159
  • [49] Green and efficient synthesis of pyranopyrazoles using [bmim][OH-] as an ionic liquid catalyst in water under microwave irradiation and investigation of their antioxidant activity
    Aliabadi, Roghayeh Sharifi
    Mahmoodi, Nosrat O.
    RSC ADVANCES, 2016, 6 (89) : 85877 - 85884
  • [50] A Convenient Stereoselective Method for Synthesis of β-Lactams Under Microwave Irradiation with [Balm] OH as a Reusable Ionic Liquid
    Bendeddouche, Souhila
    Bendeddouche, Choukry K.
    Benhaoua, Hadj
    LETTERS IN ORGANIC CHEMISTRY, 2021, 18 (12) : 929 - 935