Vanadium complexes with polypyridyl ligands: Speciation, structure and potential medicinal activity

被引：15
作者：
Hernandez, Lino [1 ]
Lorena Araujo, Mary [2 ]
Madden, Waleska [1 ]
Del Carpio, Edgar [1 ,3 ]
Lubes, Vito [1 ]
Lubes, Giuseppe [1 ]
机构：
[1] Univ Simon Bolivar USB, Lab Equilibrios Soluc, Apartado 89000, Caracas 1080, Venezuela
[2] Univ Cent Venezuela, Fac Ciencias, Ctr Equilibrios Soluc, Escuela Quim, Caracas, Venezuela
[3] Univ Cent Venezuela, Fac Farm, Escuela Dr Jemis Maria Bianco, Unidad Quim Med, Caracas, Venezuela
来源：
JOURNAL OF INORGANIC BIOCHEMISTRY | 2022年 / 229卷
关键词：
Vanadium; Vanadium-based complexes; Polypyridyl ligands; Anticancer activity; Speciation studies; Cytotoxicity; AGENT VANADOCENE DICHLORIDE; OSTEOBLAST-LIKE CELLS; AMINO-ACIDS GLYCINE; 0.6 M NA(CL); OR-EQUAL-TO; DNA CLEAVAGE; V-51; NMR; SPECTROSCOPIC CHARACTERIZATION; OXIDOVANADIUM(IV) COMPLEXES; MULTICOMPONENT POLYANIONS;
D O I：
10.1016/j.jinorgbio.2022.111712
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
This review focuses on the interaction between the essential element-vanadium with 1,10-phenanthroline and polypyridyl ligands. It starts with a summary of the prior work on speciation studies for the binary systems vanadium-phenanthroline alongside several hydrolytic studies of the metal ion. It also includes a complete overview on the different X-ray structures known to date with discussions on the potential cytotoxic activity of several vanadium-polypyridyl complexes.
引用
收藏
页数：30
相关论文
共 50 条
  • [31] Synthesis, structure and biological activity of nickel(II) complexes with mefenamato and nitrogen-donor ligands
    Totta, Xanthippi
    Papadopoulou, Aikaterini A.
    Hatzidimitriou, Antonios G.
    Papadopoulos, Athanasios
    Psomas, George
    JOURNAL OF INORGANIC BIOCHEMISTRY, 2015, 145 : 79 - 93
  • [32] Evaluation of cellular uptake, cytotoxicity and cellular ultrastructural effects of heteroleptic oxidovanadium(IV) complexes of salicylaldimines and polypyridyl ligands
    Scalese, Gonzalo
    Correia, Isabel
    Benitez, Julio
    Rostan, Santiago
    Marques, Fernanda
    Mendes, Filipa
    Matos, Antonio Pedro
    Pessoa, Joao Costa
    Gambino, Dinorah
    JOURNAL OF INORGANIC BIOCHEMISTRY, 2017, 166 : 162 - 172
  • [33] Systematic evaluation of the antitumor activity of three ruthenium polypyridyl complexes
    Jiang, Guang-Bin
    Zhang, Wen-Yao
    He, Miao
    Gu, Yi-Ying
    Bai, Lan
    Wang, Yang-Jie
    Yi, Qiao-Yan
    Du, Fan
    JOURNAL OF INORGANIC BIOCHEMISTRY, 2021, 225
  • [34] Impact of aromaticity on anticancer activity of polypyridyl ruthenium(II) complexes: synthesis, structure, DNA/protein binding, lipophilicity and anticancer activity
    Petar Čanović
    Ana Rilak Simović
    Snežana Radisavljević
    Ioannis Bratsos
    Nicola Demitri
    Marina Mitrović
    Ivanka Zelen
    Živadin D. Bugarčić
    JBIC Journal of Biological Inorganic Chemistry, 2017, 22 : 1007 - 1028
  • [35] Impact of aromaticity on anticancer activity of polypyridyl ruthenium(II) complexes: synthesis, structure, DNA/protein binding, lipophilicity and anticancer activity
    Canovic, Petar
    Simovic, Ana Rilak
    Radisavljevic, Snezana
    Bratsos, Ioannis
    Demitri, Nicola
    Mitrovic, Marina
    Zelen, Ivanka
    Bugarcic, Zivadin D.
    JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY, 2017, 22 (07): : 1007 - 1028
  • [36] Speciation in vanadium bioinorganic systems 6. Speciation study of aqueous peroxovanadates, including complexes with imidazole
    Andersson, I
    Angus-Dunne, S
    Howarth, O
    Pettersson, L
    JOURNAL OF INORGANIC BIOCHEMISTRY, 2000, 80 (1-2) : 51 - 58
  • [37] Synthesis, crystal structure, and anticancer activity of organotin(IV) complexes based on chlorine substituted aryl ligands
    Wu, Xinhua
    Wu, Lifang
    Li, Zhaoquan
    Tian, Wei
    Li, Tao
    MEDICINAL CHEMISTRY RESEARCH, 2025, : 855 - 869
  • [38] Ruthenium(II)-arene complexes with substituted picolinato ligands: Synthesis, structure, spectroscopic properties and antiproliferative activity
    Ivanovic, Ivanka
    Jovanovic, Katarina K.
    Gligorijevic, Nevenka
    Radulovic, Sinisa
    Arion, Vladimir B.
    Sheweshein, Khalil Salem A. M.
    Tesic, Zivoslav Lj.
    Grguric-Sipka, Sanja
    JOURNAL OF ORGANOMETALLIC CHEMISTRY, 2014, 749 : 343 - 349
  • [39] Cytotoxic Rhodium(III) Polypyridyl Complexes Containing the Tris(pyrazolyl)methane Coligand: Synthesis, DNA Binding Properties and Structure-Activity Relationships
    Bieda, Ruth
    Ott, Ingo
    Gust, Ronald
    Sheldrick, William S.
    EUROPEAN JOURNAL OF INORGANIC CHEMISTRY, 2009, (25) : 3821 - 3831
  • [40] New vanadium complexes with substituent-free phosphorus ligands
    Herberhold, M
    Frohmader, G
    Milius, W
    JOURNAL OF ORGANOMETALLIC CHEMISTRY, 1996, 522 (02) : 185 - 196
12345