Vanadium complexes with polypyridyl ligands: Speciation, structure and potential medicinal activity

被引：15
作者：
Hernandez, Lino [1 ]
Lorena Araujo, Mary [2 ]
Madden, Waleska [1 ]
Del Carpio, Edgar [1 ,3 ]
Lubes, Vito [1 ]
Lubes, Giuseppe [1 ]
机构：
[1] Univ Simon Bolivar USB, Lab Equilibrios Soluc, Apartado 89000, Caracas 1080, Venezuela
[2] Univ Cent Venezuela, Fac Ciencias, Ctr Equilibrios Soluc, Escuela Quim, Caracas, Venezuela
[3] Univ Cent Venezuela, Fac Farm, Escuela Dr Jemis Maria Bianco, Unidad Quim Med, Caracas, Venezuela
来源：
JOURNAL OF INORGANIC BIOCHEMISTRY | 2022年 / 229卷
关键词：
Vanadium; Vanadium-based complexes; Polypyridyl ligands; Anticancer activity; Speciation studies; Cytotoxicity; AGENT VANADOCENE DICHLORIDE; OSTEOBLAST-LIKE CELLS; AMINO-ACIDS GLYCINE; 0.6 M NA(CL); OR-EQUAL-TO; DNA CLEAVAGE; V-51; NMR; SPECTROSCOPIC CHARACTERIZATION; OXIDOVANADIUM(IV) COMPLEXES; MULTICOMPONENT POLYANIONS;
D O I：
10.1016/j.jinorgbio.2022.111712
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
This review focuses on the interaction between the essential element-vanadium with 1,10-phenanthroline and polypyridyl ligands. It starts with a summary of the prior work on speciation studies for the binary systems vanadium-phenanthroline alongside several hydrolytic studies of the metal ion. It also includes a complete overview on the different X-ray structures known to date with discussions on the potential cytotoxic activity of several vanadium-polypyridyl complexes.
引用
收藏
页数：30
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