Pathology of Striped Dolphins (Stenella coeruleoalba) Infected with Brucella ceti

被引：59
作者：
Gonzalez-Barrientos, R. [2 ]
Morales, J-A. [2 ]
Hernandez-Mora, G. [1 ]
Barquero-Calvo, E. [1 ]
Guzman-Verri, C. [1 ]
Chaves-Olarte, E. [1 ,3 ]
Moreno, E. [1 ,4 ]
机构：
[1] Univ Nacl, Escuela Med Vet, Programa Invest Enfermedades Trop, Heredia, Costa Rica
[2] Univ Nacl, Escuela Med Vet, Catedra Patol, Heredia, Costa Rica
[3] Univ Costa Rica, Fac Microbiol, Ctr Invest Enfermedades Trop, San Jose, Costa Rica
[4] Univ Costa Rica, Inst Clodomiro Picado, San Jose, Costa Rica
来源：
JOURNAL OF COMPARATIVE PATHOLOGY | 2010年 / 142卷 / 04期
关键词：
Brucella; Brucella celi; endocarditis; neurobrucellosis; placentitis; Stenella coeruleoalba; striped dolphin; TURSIOPS-TRUNCATUS; COSTA-RICA; NEUROBRUCELLOSIS; MENINGOENCEPHALITIS; STRAINS; MAMMALS; PATIENT; CATTLE;
D O I：
10.1016/j.jcpa.2009.10.017
中图分类号：
R36 [病理学];
学科分类号：
100104 ;
摘要：
Seventeen striped dolphins (Stenella coeruleoalba) displaying swimming disorders compatible with neurological syndromes were investigated for Brucella infection. Sixteen dolphins had meningoencephalomyelitis. Serum antibody against Brucella antigen was detected in all 14 animals tested and Brucella celi was isolated from eight Out of nine animals. Brucella antigen was detected in the brain by immunofluorescence, but not by immunohistochemical labelling. By contrast, Brucella antigen was demonstrated by immunohistochemistry in the trophoblast of animals with severe placentitis and in the mitral valve of animals with myocarditis. The microscopical lesions observed in the tissues of the infected dolphins were similar to those of chronic brucellosis in man. The severity of brucellosis in S. coeruleoalba indicates that this dolphin species is highly susceptible to infection by B. celi. (C) 2009 Elsevier Ltd. All rights reserved.
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收藏
页码：347 / 352
页数：6
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