Synthesis, characterization and antibacterial activities of two new Schiff bases devired from (E)-2-(((2-aminoethyl) imino) methyl) phenol (E)-2-(4-aminobut-1-enyl)-5-methylbenzamine

In the present studies two new Schiff bases ligands (E)-2-(4-aminobut-1-enyl) phenol and (E)-2-(4-aminobut-1-enyl)-5-methylaniline were synthesized. The compounds were properly characterized through FT-IR and elemental analysis and its antibacterial activities were checked against Escherichia coli, Pseudomonas aeruginosa, Bacillus cereus, Salmonella typhimurium and Staphylococcus aureus. The Schiff base ligands were screened o for their antibacterial inhibiting potentials through Disc-diffusion method, in vitro. The results indicated that as compared to control i.e. Ciprofloxacin and Erythromycin the Schiff base have significant biological activity against E. coli, while no effective inhibition was noted for other tested bacterial strains. This research highlighted Schiff bases an effective drug against the E. coli.