Intramolecular Photogeneration of a Tyrosine Radical in a Designed Protein

被引：10

作者：

Tebo, Alison G. ^{[2
]}

Quaranta, Annamaria ^{[3
]}

Herrero, Christian ^{[1
]}

Pecoraro, Vincent L. ^{[2
]}

Aukauloo, Ally ^{[1
,3
]}

机构：

[1] Univ Paris Saclay, Univ Paris Sud, Inst Chim Mol & Mat Orsay, CNRS,UMR 8182, F-91405 Orsay, France

[2] Univ Michigan, Dept Chem, Ann Arbor, MI 48109 USA

[3] CEA Saclay, IBiTecS, SB2SM, F-91191 Gif Sur Yvette, France

来源：

CHEMPHOTOCHEM | 2017年 / 1卷 / 03期

基金：

美国国家卫生研究院;

关键词：

electron transfer; photochemistry; protein design; radicals; tyrosine; COUPLED ELECTRON-TRANSFER; PHOTOSYSTEM-II; CRYSTAL-STRUCTURE; COPPER CENTER; PHOTOCHEMISTRY; OXIDATION; PHOTOPHYSICS; BINDING; MIMICS; OXYGEN;

D O I：

10.1002/cptc.201600044

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

Long-distance biological electron transfer occurs through a hopping mechanism and often involves tyrosine as a high potential intermediate, for example in the early charge separation steps during photosynthesis. Protein design allows for the development of minimal systems to study the underlying principles of complex systems. Herein, we report the development of the first ruthenium-linked designed protein for the photogeneration of a tyrosine radical by intramolecular electron transfer.

引用

页码：89 / 92

页数：4

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