Dual spectrometer system with spectral compounding for 1-μm optical coherence tomography in vivo

被引:42
作者
Cui, Dongyao [1 ,2 ,3 ]
Liu, Xinyu [1 ]
Zhang, Jing [1 ]
Yu, Xiaojun [1 ]
Ding, Sun [1 ]
Luo, Yuemei [1 ]
Gu, Jun [1 ]
Shum, Ping [1 ,2 ,3 ]
Liu, Linbo [1 ,3 ,4 ]
机构
[1] Nanyang Technol Univ, Sch Elect & Elect Engn, Singapore 639798, Singapore
[2] Nanyang Technol Univ, COFT, Photon Inst TPI, Singapore 639798, Singapore
[3] CINTRA, CNRS NTU THALES, UMI 3288, Singapore 637553, Singapore
[4] Nanyang Technol Univ, Sch Chem & Biomed Engn, Singapore 637459, Singapore
基金
新加坡国家研究基金会; 英国医学研究理事会;
关键词
Semiconductor alloys - Gallium alloys - Semiconducting indium gallium arsenide - Cameras - Indium alloys - Optical tomography - Infrared devices;
D O I
10.1364/OL.39.006727
中图分类号
O43 [光学];
学科分类号
070207 ; 0803 ;
摘要
1 mu m axial resolution spectral domain optical coherence tomography (OCT) is demonstrated for in vivo cellular resolution imaging. Output of two superluminescent diode sources is combined to provide near infrared illumination from 755 to 1105 nm. The spectral interference is detected using two spectrometers based on a Si camera and an InGaAs camera, respectively. Spectra from the two spectrometers are combined to achieve an axial resolution of 1.27 mu m in air. Imaging was conducted on zebra fish larvae to visualize cellular details. (C) 2014 Optical Society of America
引用
收藏
页码:6727 / 6730
页数:4
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