Interaction Between the R501X Filaggrin Mutation and Disease Severity Associates with Increased Staphylococcus Aureus Colonization in European American Subjects with Atopic Dermatitis

被引：1

作者：

Rafaels, Nicholas M. ^{[1
]}

Lockhart, Alexandre ^{[2
]}

Babineau, Denise C. ^{[2
]}

Artis, Keli ^{[2
]}

David, Gloria L. ^{[2
]}

Yoshida, Takeshi ^{[3
]}

Mark-Boguniewicz ^{[4
]}

Ong, Peck Y. ^{[5
]}

De Benedetto, Anna ^{[3
]}

Hanifin, Jon M. ^{[6
]}

Simpson, Eric L. ^{[6
]}

Paller, Amy S. ^{[7
]}

Guttman-Yassky, Emma ^{[8
]}

Schneider, Lynda C. ^{[9
]}

Mathias, Rasika A. ^{[10
]}

Barnes, Kathleen C. ^{[10
]}

Leung, Donald Y. ^{[4
]}

Beck, Lisa A. ^{[3
]}

机构：

[1] Univ Colorado, Ctr Biomed Informat & Personalized Med, Anschutz Med Campus, Aurora, CO USA

[2] Rho Inc, Chapel Hill, NC USA

[3] Univ Rochester, Med Ctr, Dept Dermatol, Rochester, NY 14642 USA

[4] Natl Jewish Hlth, Denver, CO USA

[5] Childrens Hosp Los Angeles USC, Los Angeles, CA USA

[6] Oregon Hlth & Sci Univ, Portland, OR 97201 USA

[7] Northwestern Univ, Feinberg Sch Med, Chicago, IL 60611 USA

[8] Icahn Sch Med Mt Sinai, Med Ctr, New York, NY 10029 USA

[9] Boston Childrens Hosp, Boston, MA USA

[10] Johns Hopkins Univ, Dept Med, Div Allergy & Clin Immunol, Baltimore, MD USA

来源：

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY | 2016年 / 137卷 / 02期

关键词：

D O I：

10.1016/j.jaci.2015.12.599

中图分类号：

R392 [医学免疫学];

学科分类号：

100102 ;

摘要：

469

引用

页码：AB143 / AB143

页数：1

共 5 条

[1] Filaggrin R501X Mutation is Associated with an Increased Susceptibility to Atopic Dermatitis and Eczema Herpeticum, and Associated Phenotypes in a European Population
Barnes, K. C.
Gao, P.
Rafaels, N. M.
Hand, T.
Boguniewicz, M.
Hata, T. R.
Schneider, L.
Hanifin, J. M.
Gallo, R. L.
Gao, L.
Yang, M.
Beaty, T. H.
Beck, L. A.
Leung, D. Y.
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2009, 123 (02) : S34 - S34
[2] Predictors of atopic dermatitis phenotypes and severity: Roles of serum immunoglobulins and filaggrin gene mutation R501X
Ercan, H.
Ispir, T.
Kirac, D.
Baris, S.
Ozen, A.
Oztezcan, S.
Cengizlier, M. R.
ALLERGOLOGIA ET IMMUNOPATHOLOGIA, 2013, 41 (02) : 86 - 93
[3] Filaggrin mutations do not associate with Staphylococcus aureus skin colonization in European American atopic dermatitis subjects
Yoshida, T.
Rafael, N.
Babineau, D.
Artis, K.
Lockhart, A.
David, G.
Boguniewicz, M.
Ong, P.
De Benedetto, A.
Hanifin, J.
Simpson, E. L.
Paller, A. S.
Guttman-Yassky, E.
Schneider, L.
Mathias, R.
Barnes, K.
Leung, D.
Beck, L. A.
JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2015, 135 : S60 - S60
[4] Filaggrin Gene Polymorphism Pro478Ser, but Not Loss-of-Function Mutations Mp.Arg501Ter or C.2282del4, Relates with Atopic Dermatitis Severity and Increased Staphylococcal aureus Colonization in Adult Patients
Rocha, Liliana
Lopes, Cristina
Fernandes, Susana
Sokhatska, Oksana
Soares, Jose
Tavaria, Freni
Pintado, Manuela
Moreira, Andre M.
Delgado, Luis
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2015, 135 (02) : AB260 - AB260
[5] Genotypic and phenotypic characterization of Staphylococcus aureus strains isolated in subjects with atopic dermatitis.: Higher prevalence of exfoliative B toxin production in lesional strains and correlation between the markers of disease intensity and colonization density
Capoluongo, E
Giglio, A
Lavieri, MM
Lesnoni-La Parola, I
Ferraro, C
Cristaudo, A
Belardi, M
Leonetti, F
Mastroianni, A
Cambieri, A
Amerio, P
Ameglio, F
JOURNAL OF DERMATOLOGICAL SCIENCE, 2001, 26 (02) : 145 - 155

← 1 →