Recent advances in bionanomaterials for liver cancer diagnosis and treatment

被引:30
作者
Chowdhury, Mohammed Mehadi Hassan [1 ,2 ]
Salazar, Christiancel Joseph J. [3 ]
Nurunnabi, Md [3 ,4 ,5 ,6 ]
机构
[1] Deakin Univ, Fac Hlth, Sch Med, 75 Pigdons Rd, Waurnponds, Vic 3216, Australia
[2] Noakhali Sci & Technol Univ, Dept Microbiol, Noakhali 3814, Bangladesh
[3] Univ Texas El Paso, Environm Sci & Engn, El Paso, TX 79968 USA
[4] Univ Texas El Paso, Biomed Engn, El Paso, TX 79968 USA
[5] Univ Texas El Paso, Sch Pharm, Dept Pharmaceut Sci, El Paso, TX 79902 USA
[6] Univ Texas El Paso, Border Biomed Res Ctr, El Paso, TX 79968 USA
关键词
MESOPOROUS SILICA NANOPARTICLES; IRON-OXIDE NANOPARTICLES; HEPATOCELLULAR-CARCINOMA; CO-DELIVERY; IN-VITRO; ARSENIC TRIOXIDE; PHOTOTHERMAL THERAPY; GOLD NANOPARTICLES; TARGETED DELIVERY; DRUG-DELIVERY;
D O I
10.1039/d1bm00167a
中图分类号
TB3 [工程材料学]; R318.08 [生物材料学];
学科分类号
0805 ; 080501 ; 080502 ;
摘要
According to the World Health Organization, liver cancer is the fourth leading cause of cancer associated with death worldwide. It demands effective treatment and diagnostic strategies to hinder its recurrence, complexities, aggressive metastasis and late diagnosis. With recent progress in nanotechnology, several nanoparticle-based diagnostic and therapeutic modalities have entered into clinical trials. With further developments in nanoparticle mediated liver cancer diagnosis and treatment, the approach holds promise for improved clinical liver cancer management. In this review, we discuss the key advances in nanoparticles that have potential for liver cancer diagnosis and treatment. We also discuss the potential of nanoparticles to overcome the limitations of existing therapeutic modalities.
引用
收藏
页码:4821 / 4842
页数:22
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