Synthesis of 3,3-disubstituted oxindoles by organoselenium-induced radical cyclizations of N-arylacrylamides

被引：10

作者：

Fu, Wei-jun ^{[1
]}

Zhu, Mei ^{[1
]}

Zou, Guang-long ^{[2
]}

机构：

[1] Luoyang Normal Univ, Coll Chem & Chem Engn, Luoyang 471022, Peoples R China

[2] Guizhou Minzu Univ, Sch Chem & Enviromental Sci, Guiyang 550025, Peoples R China

来源：

HETEROCYCLIC COMMUNICATIONS | 2015年 / 21卷 / 01期

基金：

中国国家自然科学基金;

关键词：

alkenes; cyclization; organoselenium; oxindole; radical cyclization; ACTIVATED ALKENES; FUNCTIONALIZATION;

D O I：

10.1515/hc-2014-0195

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A simple and practical approach to oxindole derivatives via organoselenium-induced radical cyclizations of N-arylacrylamides has been developed. This method provides a convenient access to a variety of selenium-containing oxindoles in good to excellent yields under relatively mild reaction conditions. As one of its notable features, the radical process allows for the direct formation of a Se-C bond and the construction of a oxindole ring in one reaction.

引用

页码：9 / 12

页数：4