Considering patients' values and preferences in comparative effectiveness research (CER) is one of the main challenges in ophthalmology (value-based medicine). This article defines core terms in CER. The concept of patient-relevant (or patient-important) outcomes is distinguished from patient-reported outcomes (PRO) by means of examples in the field of ophthalmology. In order to be able to give a consistant recommendation if an intervention leads to conflicting results for different outcomes (trade-off), a ranking of outcomes will be necessary. Examples of studies in glaucoma patients are provided that demonstrate the possibilities of ranking of outcomes based on patient preferences.
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Brigham & Womens Hosp, Div Allergy & Immunol, Boston, MA USA
Harvard Med Sch, Boston, MA USABrigham & Womens Hosp, Div Allergy & Immunol, Boston, MA USA
Ramirez, Lourdes G.
Louisias, Margee
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Brigham & Womens Hosp, Div Allergy & Immunol, Boston, MA USA
Harvard Med Sch, Boston, MA USABrigham & Womens Hosp, Div Allergy & Immunol, Boston, MA USA
Louisias, Margee
Ogbogu, Princess U.
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Univ Hosp Rainbow Babies & Childrens Hosp, Div Pediat Allergy Immunol & Rheumatol, Cleveland, OH USA
Case Western Reserve Univ, Sch Med, Dept Orthopaed, Cleveland, OH USABrigham & Womens Hosp, Div Allergy & Immunol, Boston, MA USA
Ogbogu, Princess U.
Stinson, Alanna
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Univ Chicago, Dept Pediat, Sect Allergy Immunol & Pediat Pulmonol, 5837 S Maryland Ave, Chicago, IL 60637 USABrigham & Womens Hosp, Div Allergy & Immunol, Boston, MA USA
Stinson, Alanna
Gupta, Ruchi
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Northwestern Univ, Inst Publ Hlth & Med, Ctr Food Allergy & Asthma Res, Feinberg Sch Med, Chicago, IL USA
Ann & Robert H Lurie Childrens Hosp Chicago, Div Adv Gen Pediat & Primary Care, Chicago, IL USABrigham & Womens Hosp, Div Allergy & Immunol, Boston, MA USA
Gupta, Ruchi
Sansweet, Samantha
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Northwestern Univ, Inst Publ Hlth & Med, Ctr Food Allergy & Asthma Res, Feinberg Sch Med, Chicago, IL USA
Ann & Robert H Lurie Childrens Hosp Chicago, Div Adv Gen Pediat & Primary Care, Chicago, IL USABrigham & Womens Hosp, Div Allergy & Immunol, Boston, MA USA
Sansweet, Samantha
Singh, Tarandeep
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Univ Penn, Perelman Sch Med, Sect Allergy & Immunol, Div Pulm Allergy & Crit Care Med, Philadelphia, PA USABrigham & Womens Hosp, Div Allergy & Immunol, Boston, MA USA
Singh, Tarandeep
Apter, Andrea
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Univ Penn, Perelman Sch Med, Sect Allergy & Immunol, Div Pulm Allergy & Crit Care Med, Philadelphia, PA USABrigham & Womens Hosp, Div Allergy & Immunol, Boston, MA USA
Apter, Andrea
Jones, Bridgette L.
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Univ Missouri Kansas City, Sch Med, Dept Pediat, Kansas City, MO USA
Childrens Mercy Hosp, Sect Allergy Immunol, Kansas City, MO USA
Childrens Mercy Hosp, Div Pediatr Clin Pharmacol & Therapeut Innovat, Kansas City, MO USABrigham & Womens Hosp, Div Allergy & Immunol, Boston, MA USA
Jones, Bridgette L.
Nyenhuis, Sharmilee M.
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Univ Chicago, Dept Pediat, Sect Allergy Immunol & Pediat Pulmonol, 5837 S Maryland Ave, Chicago, IL 60637 USABrigham & Womens Hosp, Div Allergy & Immunol, Boston, MA USA
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Univ Sussex, Brighton & Sussex Med Sch, Canc Res UK Psychosocial Oncol Grp, Brighton BN1 9QG, E Sussex, EnglandUniv Sussex, Brighton & Sussex Med Sch, Canc Res UK Psychosocial Oncol Grp, Brighton BN1 9QG, E Sussex, England
Ballinger, R. S.
Fallowfield, L. J.
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Univ Sussex, Brighton & Sussex Med Sch, Canc Res UK Psychosocial Oncol Grp, Brighton BN1 9QG, E Sussex, EnglandUniv Sussex, Brighton & Sussex Med Sch, Canc Res UK Psychosocial Oncol Grp, Brighton BN1 9QG, E Sussex, England