Photoaging Prevention and Topical Treatments

被引：42

作者：

Antoniou, Christina ^{[1
]}

Kosmadaki, Maria G. ^{[1
]}

Stratigos, Alexandros J. ^{[1
]}

Katsambas, Andreas D. ^{[1
]}

机构：

[1] Univ Athens, Sch Med, Dept Dermatol, Andreas Sygros Hosp, Athens 16121, Greece

来源：

AMERICAN JOURNAL OF CLINICAL DERMATOLOGY | 2010年 / 11卷 / 02期

关键词：

TRETINOIN EMOLLIENT CREAM; SKIN IN-VIVO; INCREASES TYPE-I; ASCORBIC-ACID; PHOTODAMAGED SKIN; DOUBLE-BLIND; RETINOIC ACID; GLYCOLIC ACID; VITAMIN-C; MESSENGER-RNA;

D O I：

10.2165/11530210-000000000-00000

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

A rapidly increasing number of people visit dermatologists for the prevention and treatment of aging skin. Sun avoidance and sunscreen use are widely accepted strategies of primary prevention against photoaging. Convincing evidence shows that topical application of retinoids has an effect on reversing, at least partially, mild to moderate photodamage. Antioxidants and alpha-hydroxy acids can alter the skin structure and function. Enzymes that repair DNA damage or oligonucleotides that enhance the endogenous capacity for DNA damage repair may prove to be future preventive/therapeutic interventions for aging skin.

引用

页码：95 / 102

页数：8

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