Benefit of IVIG for long-standing ataxic sensory neuronopathy with Sjogren's syndrome

被引：85

作者：

Takahashi, Y

Takata, T

Hoshino, M

Sakurai, M

Kanazawa, I

机构：

[1] Univ Tokyo, Grad Sch Med, Dept Neurol, Bunkyo Ku, Tokyo 1138655, Japan

[2] Kobe Univ, Sch Med, Dept Geriatr Med, Kobe, Hyogo 650, Japan

[3] Teikyo Univ, Sch Med, Dept Physiol, Tokyo 173, Japan

来源：

NEUROLOGY | 2003年 / 60卷 / 03期

关键词：

D O I：

10.1212/01.WNL.0000046680.47883.7D

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Ataxic sensory neuronopathy with Sjogren's syndrome is a devastating neurologic complication for which there is no established treatment. IV immunoglobulin (IVIG) was given to five patients with severe disabilities for an average of 12 years. Four patients showed remarkable improvement, two of whom responded after the first course. The authors conclude that IVIG is safe and effective to treat even chronically debilitated patients who have the disease, presumably because it ameliorates smoldering inflammation.

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页码：503 / 505

页数：3

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