Can Cobalt(II) and Chromium(III) Ions Released from Joint Prostheses Influence the Friction Coefficient?

被引：22

作者：

Hedberg, Y. S. ^{[1
,2
]}

Pettersson, M. ^{[3
]}

Pradhan, S. ^{[1
]}

Wallinder, I. Odnevall ^{[1
]}

Rutland, M. W. ^{[1
,4
]}

Persson, C. ^{[3
]}

机构：

[1] KTH Royal Inst Technol, Sch Chem Sci & Engn, Dept Chem, Div Surface & Corros Sci, Drottning Kristinas Vag 51, SE-10044 Stockholm, Sweden

[2] Karolinska Inst, Inst Environm Med, Unit Occupat & Environm Dermatol, SE-17177 Stockholm, Sweden

[3] Uppsala Univ, Dept Engn Sci, Div Appl Mat Sci, S-75121 Uppsala, Sweden

[4] SP Tech Res Inst Sweden, Chem Mat & Surfaces, SE-11486 Stockholm, Sweden

来源：

ACS BIOMATERIALS SCIENCE & ENGINEERING | 2015年 / 1卷 / 08期

基金：

瑞典研究理事会;

关键词：

hip joint; replacement; friction; protein-metal binding; CoCrMo; alloy tribology; TRIBOCHEMICAL REACTION; BOUNDARY LUBRICATION; WEAR DEBRIS; METAL; BINDING; SERUM; NANOPARTICLES;

D O I：

10.1021/acsbiomaterials.5b00183

中图分类号：

TB3 [工程材料学]; R318.08 [生物材料学];

学科分类号：

0805 ; 080501 ; 080502 ;

摘要：

Cobalt chromium molybdenum alloys (CoCrMo) are commonly used as articulating components in joint prostheses. In this tribocorrosive environment, wear debris and metal ionic species are released and interact with proteins, possibly resulting in protein aggregation. This study aimed to investigate whether this could have an effect on the friction coefficient in a typical material couple, namely CoCrMo-on-polyethylene. It was confirmed that both Co(II) and Cr(III) ions, and their combination, at concentrations relevant for the metal release situation, resulted in protein aggregation and its concomitant precipitation, which increased the friction coefficient. Future studies should identify the clinical importance of these findings.

引用

页码：617 / 620

页数：4

共 27 条

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