Anti-TIF1γ antibody-positive dermatomyositis associated with durvalumab administration in a patient with lung and oesophageal cancers

被引:4
|
作者
Imai, Ryosuke [1 ]
Ikemura, Sumie [2 ]
Jinta, Torahiko [1 ]
机构
[1] St Lukes Int Hosp, Dept Pulm Med, Thorac Ctr, 9-1 Akashi Cho, Chuo City, Tokyo 1048560, Japan
[2] St Lukes Int Hosp, Dept Dermatol, Tokyo, Japan
来源
RESPIROLOGY CASE REPORTS | 2021年 / 9卷 / 04期
关键词
Dermatomyositis; durvalumab; immune checkpoint inhibitor; intravenous immunoglobulin;
D O I
10.1002/rcr2.736
中图分类号
R56 [呼吸系及胸部疾病];
学科分类号
摘要
We report a case of anti-transcriptional intermediary factor 1 gamma (TIF1 gamma) antibody-positive dermatomyositis following durvalumab treatment. The patient was successfully treated with pulse steroid therapy, high-dose intravenous immunoglobulin (IVIg), and tacrolimus. Durvalumab may induce dermatomyositis, and early diagnosis and aggressive therapy are crucial to prevent severe dermatomyositis, which is potentially treatable.
引用
收藏
页数:3
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