An in Vitro Experimental Study on the Antimicrobial Activity of Silicone Oil against Anaerobic Bacteria

被引：12
作者：
Arici, Ceyhun [1 ]
Aras, Cengiz [1 ]
Tokman, Hrisi Bahar [2 ]
Torun, Muzeyyen Mamal [3 ]
机构：
[1] Istanbul Univ, Dept Ophthalmol, Cerrahpasa Med Fac, Istanbul, Turkey
[2] Istanbul Univ, Dept Med Microbiol, Cerrahpasa Med Fac, Istanbul, Turkey
[3] Bahcesehir Univ, Dept Med Microbiol, Fac Med, Istanbul, Turkey
来源：
OCULAR IMMUNOLOGY AND INFLAMMATION | 2016年 / 24卷 / 02期
关键词：
Anaerobic bacteria; antimicrobial resistance; antimicrobial susceptibility; endophthalmitis; silicone oil; ONSET PSEUDOPHAKIC ENDOPHTHALMITIS; COMPLEX RETINAL DETACHMENTS; PROPIONIBACTERIUM-ACNES; BIOFILM FORMATION; CATARACT-SURGERY; FILLED EYE; BIOMATERIALS; MULTICENTER; REPAIR; AGENTS;
D O I：
10.3109/09273948.2014.971973
中图分类号：
R77 [眼科学];
学科分类号：
100212 ;
摘要：
Purpose: To investigate the in vitro antimicrobial activity of silicone oil against anaerobic agents, specifically Propionibacterium acnes, Peptostreptococcus spp., Peptostreptococcus anaerobius, Bacteroides fragilis, Fuobacterium spp., and Clostridium tertium. Method: A 0.5 McFarland turbidity of Propionibacterium acnes, Peptostreptococcus spp., Peptostreptococcus anaerobius, Bacteroides fragilis, Fuobacterium spp., and Clostridium tertium was prepared, and 0.1 mL was inoculated into 0.9 mL of silicone oil. Control inoculations were performed in anaerobic blood agar and fluid thioglycollate medium without silicone oil. Results: Propionibacterium acnes retained their viability on the 3rd day in the presence of silicone oil. In total, 9.7 x 10(6) colonies were enumerated from 1 mL of silicone oil. After a prolonged incubation of 7 days, the number of colonies observed was 9.2 x 10(6). The other bacteria disappeared after the 3rd day of incubation in silicone oil. Conclusions: Propionibacterium acnes, which is the most common chronic postoperative endophthalmitis agent, is thought to be resistant to silicone oil.
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收藏
页码：173 / 177
页数：5
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