Myocyte and myogenic stem cell transplantation in the heart

被引：172

作者：

Dowell, JD

Rubart, M

Pasumarthi, KBS

Soonpaa, MH

Field, LJ

机构：

[1] Indiana Univ, Sch Med, Wells Ctr Pediat Res, Indianapolis, IN 46202 USA

[2] Indiana Univ, Sch Med, Krannert Inst Cardiol, Indianapolis, IN 46202 USA

来源：

CARDIOVASCULAR RESEARCH | 2003年 / 58卷 / 02期

关键词：

cellular transplantation; cardiomyocytes; skeletal myoblasts; stem cells; heart failure;

D O I：

10.1016/S0008-6363(03)00254-2

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Cellular transplantation is emerging as a potential mechanism with which to augment myocyte number in diseased hearts. To date a number of cell types have been shown to successfully engraft into the myocardium, including fetal, neonatal, and embryonic stem cell-derived cardiomyocytes, skeletal myoblasts, and stem cells with apparent cardiomyogenic potential. Here we provide a review of studies wherein myocytes or stem cells with myogenic potential have been transplanted into the heart. In addition, issues pertaining to the tracking and functional consequences of cell transplantation are discussed. (C) 2003 European Society of Cardiology. Published by Elsevier Science B.V. All rights reserved.

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收藏

页码：336 / 350

页数：15

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