Lenalidomide differently modulates CD20 antigen surface expression on chronic lymphocytic leukemia B-cells

被引:2
作者
D'Arena, Giovanni [1 ]
Ruggieri, Vitalba [1 ]
D'Auria, Fiorella [1 ]
La Rocca, Francesco [1 ]
Simeon, Vittorio [1 ]
Statuto, Teodora [1 ]
Caivano, Antonella [1 ]
Telesca, Donatella [1 ]
Del Vecchio, Luigi [2 ]
Musto, Pellegrino [1 ]
机构
[1] IRCCS Referral Canc Ctr Basilicata, Potenza, Italy
[2] Univ Naples Federico II, CEINGE Inst Adv Biotechnol, I-80138 Naples, Italy
关键词
RITUXIMAB;
D O I
10.3109/10428194.2014.999329
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
引用
收藏
页码:2458 / 2459
页数:2
相关论文
共 9 条
[1]   Phase II Study of Lenalidomide and Rituximab As Salvage Therapy for Patients With Relapsed or Refractory Chronic Lymphocytic Leukemia [J].
Badoux, Xavier C. ;
Keating, Michael J. ;
Wen, Sijin ;
Wierda, William G. ;
O'Brien, Susan M. ;
Faderl, Stefan ;
Sargent, Rachel ;
Burger, Jan A. ;
Ferrajoli, Alessandra .
JOURNAL OF CLINICAL ONCOLOGY, 2013, 31 (05) :584-591
[2]  
D'Arena G, 2000, AM J HEMATOL, V64, P275
[3]   Lenalidomide Induces Capping of CD20 and Cytoskeleton Proteins, to Enhance Rituximab Immune Recognition of Malignant B-Cells [J].
Gaidarova, Svetlana ;
Mendy, Derek ;
Heise, Carla ;
Aukerman, Sharon Lea ;
Daniel, Tom ;
Chopra, Rajesh ;
Lopez-Girona, Antonia .
BLOOD, 2010, 116 (21) :1173-1173
[4]   Treating chronic lymphocytic leukemia with thalidomide and lenalidomide [J].
Giannopoulos, Krzysztof ;
Mertens, Daniel ;
Stilgenbauer, Stephan .
EXPERT OPINION ON PHARMACOTHERAPY, 2011, 12 (18) :2857-2864
[5]   How does lenalidomide target the chronic lymphocytic leukemia microenvironment? [J].
Kater, Arnon P. ;
Tonino, Sanne H. ;
Egle, Alexander ;
Ramsay, Alan G. .
BLOOD, 2014, 124 (14) :2184-2189
[6]   Lenalidomide down-regulates the CD20 antigen and antagonizes direct and antibody-dependent cellular cytotoxicity of rituximab on primary chronic lymphocytic leukemia cells [J].
Lapalombella, Rosa ;
Yu, Bo ;
Triantafillou, Georgia ;
Liu, Qing ;
Butchar, Jonathan P. ;
Lozanski, Gerard ;
Ramanunni, Asha ;
Smith, Lisa L. ;
Blum, William ;
Andritsos, Leslie ;
Wang, Da-Sheng ;
Lehman, Amy ;
Chen, Ching-Shih ;
Johnson, Amy J. ;
Marcucci, Guido ;
Lee, Robert J. ;
Lee, L. James ;
Tridandapani, Susheela ;
Muthusamy, Natarajan ;
Byrd, John C. .
BLOOD, 2008, 112 (13) :5180-5189
[7]   Immune dysfunction in chronic lymphocytic leukemia T cells and lenalidomide as an immunomodulatory drug [J].
Ramsay, Alan G. ;
Gribben, John G. .
HAEMATOLOGICA-THE HEMATOLOGY JOURNAL, 2009, 94 (09) :1198-1202
[8]   Immunomodulatory drugs stimulate natural killer-cell function, alter cytokine production by dendritic cells, and inhibit angiogenesis enhancing the anti-tumour activity of rituximab in vivo [J].
Reddy, Nishitha ;
Hernandez-Ilizaliturri, Francisco J. ;
Deeb, George ;
Roth, Mark ;
Vaughn, Mary ;
Knight, Joy ;
Wallace, Paul ;
Czuczman, Myron S. .
BRITISH JOURNAL OF HAEMATOLOGY, 2008, 140 (01) :36-45
[9]   Rituximab: Mechanism of Action [J].
Weiner, George J. .
SEMINARS IN HEMATOLOGY, 2010, 47 (02) :115-123