Optic Neuritis Following Hepatitis B Vaccination in a 9-year-old Girl

被引:19
作者
Erguven, Muferet [2 ]
Guven, Sirin [1 ]
Akyuz, Umit [3 ]
Bilgic, Olcay [2 ]
Laloglu, Fuat [2 ]
机构
[1] Umraniye Egitim & Arastirma Hastanesi, Istanbul, Turkey
[2] Goztepe Educ & Res Hosp, Istanbul, Turkey
[3] Zeynep Kamil Educ & Res Hosp, Istanbul, Turkey
关键词
children; hepatitis B vaccine; hepatitis B virus; optic neuritis; ADVERSE EVENTS; RISK; CHILDHOOD; CHILDREN;
D O I
10.1016/S1726-4901(09)70435-6
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Hepatitis B vaccination can prevent hepatitis B virus infection and its serious consequences, including liver cancer and cirrhosis. Serious side effects reported after receiving hepatitis B vaccination are very uncommon. A majority of the ophthalmological complications seen following hepatitis B vaccination consist of vision loss, optic neuritis, papillary edema, uveitis, acute placoid pigment epitheliopathy and central vein occlusion. We present a 9-year-old girl who was referred to our hospital with decrease in vision and pain in the left eye a week after hepatitis B vaccination. A diagnosis of vaccine-induced optic neuritis was made. The clinical picture improved after systemic corticosteroid treatment. Acute optic neuritis might be a rare complication of hepatitis B vaccination. Parents should be aware of the potential serious side effects of the vaccine. [J Chin Med Assoc 2009;72(11):594-597]
引用
收藏
页码:594 / 597
页数:4
相关论文
共 17 条
[1]   Bilateral retrobulbar optic neuritis with hepatitis B vaccination [J].
Albitar, S ;
Bourgeon, B ;
Genin, R ;
FenChong, M ;
NGuyen, P ;
Serveaux, MO ;
Atchia, H ;
Schohn, D .
NEPHROLOGY DIALYSIS TRANSPLANTATION, 1997, 12 (10) :2169-2170
[2]   SERIOUS HEPATITIS-B VACCINE ADVERSE REACTIONS, ARE THEY IMMUNE-MEDIATED [J].
CARMELI, Y ;
DEMEDINA, T .
VACCINE, 1993, 11 (13) :1358-1359
[3]   Universal hepatitis B vaccination in Taiwan and the incidence of hepatocellular carcinoma in children [J].
Chang, MH ;
Chen, CJ ;
Lai, MS ;
Hsu, HM ;
Wu, TC ;
Kong, MS ;
Liang, DC ;
Shau, WY ;
Chen, DS .
NEW ENGLAND JOURNAL OF MEDICINE, 1997, 336 (26) :1855-1859
[4]   Hepatitis B vaccination: The key towards elimination and eradication of hepatitis B [J].
Chen, Ding-Shinn .
JOURNAL OF HEPATOLOGY, 2009, 50 (04) :805-816
[5]  
Classen B, 1996, NEW ZEAL MED J, V109, P195
[6]   Vaccinations and risk of central nervous system demyelinating diseases in adults [J].
DeStefano, F ;
Verstraeten, T ;
Jackson, LA ;
Okoro, CA ;
Benson, P ;
Black, SB ;
Shinefield, HR ;
Mullooly, JP ;
Likosky, W ;
Chen, RT .
ARCHIVES OF NEUROLOGY, 2003, 60 (04) :504-509
[7]   A case-control study of serious autoimmune adverse events following hepatitis B immunization [J].
Geier, DA ;
Geier, MR .
AUTOIMMUNITY, 2005, 38 (04) :295-301
[8]  
Geier MR, 2004, CLIN EXP RHEUMATOL, V22, P749
[9]   Hepatitis B vaccination and the risk of childhood-onset multiple sclerosis [J].
Mikaeloff, Yann ;
Caridade, Guillaume ;
Rossier, Melanie ;
Suissa, Samy ;
Tardieu, Marc .
ARCHIVES OF PEDIATRICS & ADOLESCENT MEDICINE, 2007, 161 (12) :1176-1182
[10]   Hepatitis B vaccine and the risk of CNS inflammatory demyelination in childhood [J].
Mikaeloff, Yann ;
Caridade, Guillaume ;
Suissa, Samy ;
Tardieu, Marc .
NEUROLOGY, 2009, 72 (10) :873-880