Olive oil and cancer

被引：0

作者：

López, S ^{[1
]}

Pacheco, YM ^{[1
]}

Bermúdez, B ^{[1
]}

Abia, R ^{[1
]}

Muriana, FJG ^{[1
]}

机构：

[1] CSIC, Inst Grasa, E-41080 Seville, Spain

来源：

GRASAS Y ACEITES | 2004年 / 55卷 / 01期

关键词：

olive oil; monounsaturated fatty acids; minor compounds; antioxidants; phenolics; Mediterranean diet;

D O I：

暂无

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

In the last years, numerous studies have examined the association of dietary fat and cancer. Polyunsaturated fatty acids (PUFA) from n-6 family display a strong promoting effect, this may be partially due to the especially prone to lipid peroxidation of PUFA that leads to formation of aldehydes, which react with DNA bases, forming genotoxic exocyclic etheno(epsilon)-adducts. On the contrary, there are growing evidences that monounsaturated oils, like olive oil, may be associated with a decreased risk of some cancers. However, the epidemiological data do not fully agree with the experimental ones previously published. Minor compounds from (extra virgin) olive oil, mainly phenolics like hydroxytyrosol and tocopherol, are antioxidants and radical scavenging. They can minimize the amount of reactive oxygen species (ROS) generated by fatty acid peroxidation and in the case of monounsaturated fatty acids (MUFA) the DNA damage can be reduced by a lower lipid peroxidation.

引用

页码：33 / 41

页数：9

共 84 条

[1] Phytosterols reduce in vitro metastatic ability of MDA-MB-231 human breast cancer cells [J].