Aging with HIV in the ART era

被引：56
作者：
Kaplan-Lewis, Emma [1 ]
Aberg, Judith A. [1 ]
Lee, Mikyung [1 ]
机构：
[1] Icahn Sch Med Mt Sinai, Div Infect Dis, One Gustave L Levy Pl,Box 1090, New York, NY 10029 USA
来源：
SEMINARS IN DIAGNOSTIC PATHOLOGY | 2017年 / 34卷 / 04期
关键词：
HIV; Aging; Accelerated aging; Inflammation; Inflammaging; Multimorbidity; Polypathology; HUMAN-IMMUNODEFICIENCY-VIRUS; HEPATITIS-B-VIRUS; OBSTRUCTIVE PULMONARY-DISEASE; MONTREAL COGNITIVE ASSESSMENT; CORONARY-HEART-DISEASE; VITAMIN-D DEFICIENCY; INFECTED PATIENTS; RISK-FACTORS; LUNG-CANCER; ANTIRETROVIRAL THERAPY;
D O I：
10.1053/j.semdp.2017.04.002
中图分类号：
R446 [实验室诊断]; R-33 [实验医学、医学实验];
学科分类号：
1001 ;
摘要：
In the current era of therapy for human immunodeficiency virus (HIV), life expectancy for persons living with HIV (PLWH) approaches that of the general population. This newly prolonged survival among PLWH is associated with an increased prevalence of comorbidities due to the inflammation, immune activation and immune senescence associated with HIV infection. Higher prevalence of tobacco and alcohol use, co infection with viral hepatitis and traditional cardiovascular risk factors such as hypertension and hyperlipidemia contribute as well. In this review, we hope to describe the current comorbidities occurring among PLWH and bring increased awareness for conditions that may otherwise not be considered given the younger age at time of presentation. (C) 2017 Elsevier Inc. All rights reserved.
引用
收藏
页码：384 / 397
页数：14
相关论文
共 223 条
[31]   Hypothalamic-PituitaryAdrenal Axis in HIV Infection and Disease [J].
Chrousos, George P. ;
Zapanti, Evangelia D. .
ENDOCRINOLOGY AND METABOLISM CLINICS OF NORTH AMERICA, 2014, 43 (03) :791-+
[32]   Epidemiology of Hepatitis B Virus Infection in a US Cohort of HIV-Infected Individuals during the Past 20 Years [J].
Chun, Helen M. ;
Fieberg, Ann M. ;
Hullsiek, Katherine Huppler ;
Lifson, Alan R. ;
Crum-Cianflone, Nancy F. ;
Weintrob, Amy C. ;
Ganesan, Anuradha ;
Barthel, Robert V. ;
Bradley, William P. ;
Agan, Brian K. ;
Landrum, Michael L. .
CLINICAL INFECTIOUS DISEASES, 2010, 50 (03) :426-436
[33]   Hepatitis C guidance: AASLD-IDSA recommendations for testing, managing, and treating adults infected with hepatitis C virus [J].
Chung, Raymond T. ;
Davis, Gary L. ;
Jensen, Donald M. ;
Masur, Henry ;
Saag, Michael S. ;
Thomas, David L. ;
Aronsohn, Andrew I. ;
Charlton, Michael R. ;
Feld, Jordan J. ;
Fontana, Robert J. ;
Ghany, Marc G. ;
Godofsky, Eliot W. ;
Graham, Camilla S. ;
Kim, Arthur Y. ;
Kiser, Jennifer J. ;
Kottilil, Shyam ;
Marks, Kristen M. ;
Martin, Paul ;
Mitruka, Kiren ;
Morgan, Timothy R. ;
Naggie, Susanna ;
Raymond, Daniel ;
Reau, Nancy S. ;
Schooley, Robert T. ;
Sherman, Kenneth E. ;
Sulkowski, Mark S. ;
Vargas, Hugo E. ;
Ward, John W. ;
Wyles, David L. .
HEPATOLOGY, 2015, 62 (03) :932-954
[34]  
Clark RA, 1999, J ACQ IMMUN DEF SYND, V23, P99
[35]   Statin Utilization and Recommendations Among HIV- and HCV-infected Veterans: A Cohort Study [J].
Clement, Meredith E. ;
Park, Lawrence P. ;
Navar, Ann Marie ;
Okeke, Nwora Lance ;
Pencina, Michael J. ;
Douglas, Pamela S. ;
Naggie, Susanna .
CLINICAL INFECTIOUS DISEASES, 2016, 63 (03) :407-413
[36]   Sexual hormones in HIV-infected patients: the influence of antiretroviral therapy [J].
Collazos, J ;
Martinez, E ;
Mayo, J ;
Ibarra, S .
AIDS, 2002, 16 (06) :934-937
[37]   How harmful is hazardous alcohol use and abuse in HIV infection: Do health care providers know who is at risk? [J].
Conigliaro, J ;
Gordon, AJ ;
McGinnis, KA ;
Rabeneck, L ;
Justice, AC .
JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES, 2003, 33 (04) :521-525
[38]   Role of alcohol in determining human immunodeficiency virus (HIV)-relevant outcomes - A conceptual model to guide the implementation of evidence-based interventions into practice [J].
Conigliaro, Joseph ;
Justice, Amy C. ;
Gordon, Adam J. ;
Bryant, Kendall .
MEDICAL CARE, 2006, 44 (08) :S1-S6
[39]  
Crane HM, 2016, COM ADV DRUG REACT H
[40]  
Crane HM, 2017, JAMA CARDIOL 0104
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