Aging with HIV in the ART era

被引：55

作者：

Kaplan-Lewis, Emma ^{[1
]}

Aberg, Judith A. ^{[1
]}

Lee, Mikyung ^{[1
]}

机构：

[1] Icahn Sch Med Mt Sinai, Div Infect Dis, One Gustave L Levy Pl,Box 1090, New York, NY 10029 USA

来源：

SEMINARS IN DIAGNOSTIC PATHOLOGY | 2017年 / 34卷 / 04期

关键词：

HIV; Aging; Accelerated aging; Inflammation; Inflammaging; Multimorbidity; Polypathology; HUMAN-IMMUNODEFICIENCY-VIRUS; HEPATITIS-B-VIRUS; OBSTRUCTIVE PULMONARY-DISEASE; MONTREAL COGNITIVE ASSESSMENT; CORONARY-HEART-DISEASE; VITAMIN-D DEFICIENCY; INFECTED PATIENTS; RISK-FACTORS; LUNG-CANCER; ANTIRETROVIRAL THERAPY;

D O I：

10.1053/j.semdp.2017.04.002

中图分类号：

R446 [实验室诊断]; R-33 [实验医学、医学实验];

学科分类号：

1001 ;

摘要：

In the current era of therapy for human immunodeficiency virus (HIV), life expectancy for persons living with HIV (PLWH) approaches that of the general population. This newly prolonged survival among PLWH is associated with an increased prevalence of comorbidities due to the inflammation, immune activation and immune senescence associated with HIV infection. Higher prevalence of tobacco and alcohol use, co infection with viral hepatitis and traditional cardiovascular risk factors such as hypertension and hyperlipidemia contribute as well. In this review, we hope to describe the current comorbidities occurring among PLWH and bring increased awareness for conditions that may otherwise not be considered given the younger age at time of presentation. (C) 2017 Elsevier Inc. All rights reserved.

引用

页码：384 / 397

页数：14

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