Roles of DNA Repair Proteins in Telomere Maintenance

被引：10

作者：

Ueno, Masaru ^{[1
]}

机构：

[1] Hiroshima Univ, Grad Sch Adv Sci Matter, Dept Mol Biotechnol, Higashihiroshima 7398530, Japan

来源：

BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY | 2010年 / 74卷 / 01期

关键词：

telomere; DNA repair; replication protein A (RPA); RecQ helicase; Mre11-Rad50-Nbs1; complex; SCHIZOSACCHAROMYCES-POMBE RAD32; SINGLE-STRAND OVERHANG; FISSION YEAST; SACCHAROMYCES-CEREVISIAE; WERNER-SYNDROME; RECQ HELICASES; HUMAN-CELLS; HOMOLOGOUS RECOMBINATION; MAMMALIAN TELOMERES; PROTECTS TELOMERES;

D O I：

10.1271/bbb.90682

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Telomeres are protected and maintained by telomere-specific proteins. In addition, proteins involved in DNA repair, such as Mre11-Rad50-Nbs1 complex, RPA, and RecQ helicase, are also involved in telomere maintenance. In this review, the roles of these proteins in telomere maintenance and their functional relationships to the telomere-specific proteins will be discussed.

引用

页码：1 / 6

页数：6

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