Medical and surgical management of obesity and diabetes: what's new?

被引：26

作者：

Ammori, B. J. ^{[1
]}

Skarulis, M. C. ^{[2
]}

Soran, H. ^{[5
,6
]}

Syed, A. A. ^{[5
,7
]}

Eledrisi, M. ^{[3
,4
]}

Malik, R. A. ^{[3
,4
,5
]}

机构：

[1] King Hussein Canc Ctr, Dept Surg, Amman, Jordan

[2] Hamad Med Corp, Natl Obes Treatment Ctr, Doha, Qatar

[3] Hamad Med Corp, Dept Diabet & Endocrinol, Doha, Qatar

[4] Weill Cornell Med Qatar, Dept Med, Doha, Qatar

[5] Univ Manchester, Fac Biol Med & Hlth, Manchester, Lancs, England

[6] Manchester Univ NHS Fdn Trust, Dept Med, Manchester, Lancs, England

[7] Salford Royal NHS Fdn Trust, Dept Diabet & Endocrinol, Salford, Lancs, England

来源：

DIABETIC MEDICINE | 2020年 / 37卷 / 02期

关键词：

LAPAROSCOPIC SLEEVE GASTRECTOMY; Y-GASTRIC BYPASS; BARIATRIC SURGERY; DOUBLE-BLIND; WEIGHT-LOSS; TYPE-2; METAANALYSIS; ASSOCIATION; MELLITUS; OUTCOMES;

D O I：

10.1111/dme.14215

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

We conducted a narrative review of the medical and surgical management of people with obesity and diabetes. Results of this review showed that a 5-10% loss in body weight can be achieved with a change in lifestyle, diet and behaviour and with approved pharmacological therapies in people with obesity and diabetes. New targeted therapies are now available for patients with previously untreatable genetic causes of obesity. Compared to medical treatment, metabolic and bariatric surgery is associated with significantly higher rates of remission from type 2 diabetes and lower rates of incident macrovascular and microvascular complications and mortality. The National Institute for Health and Care Excellence and the American Diabetes Association endorse metabolic and bariatric surgery in obese adults with type 2 diabetes and there may also be a role for this in obese individuals with type 1 diabetes. The paediatric committee of the American Society for Metabolic and Bariatric Surgery have recommended metabolic and bariatric surgery in obese adolescents with type 2 diabetes. Earlier and more aggressive treatment with metabolic and bariatric surgery in obese or overweight people with diabetes can improve morbidity and mortality.

引用

页码：203 / 210

页数：8

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