Thymoma in children - Report of two cases and review of literature

被引:20
作者
Dhall, G [1 ]
Ginsburg, HB [1 ]
Bodenstein, L [1 ]
Fefferman, NR [1 ]
Greco, MA [1 ]
Chang, MW [1 ]
Gardner, S [1 ]
机构
[1] St Peters Univ Hosp, Div Pediat Hematol Oncol, New Brunswick, NJ 08903 USA
关键词
thymoma; children; nevus sebaceus;
D O I
10.1097/01.mph.0000141069.38462.d8
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Thymoma is an uncommon tumor of childhood. Stage of the tumor is an independent prognostic factor for survival. Surgery is the treatment of choice for stage 1 and stage 11 tumors. Chemotherapy is reserved for patients with refractory or metastatic disease. Thymomas are moderately radiosensitive. However, radiation therapy is not an attractive option for children due to its side-effects on developing organs. The authors describe 2 children with completely encapsulated thymoma who were successfully treated with Surgery alone. Both patients remain free of disease 3 years after Surgery. One of the patients also has nevus sebaceous. The authors also discuss the possible association between the two disease entities.
引用
收藏
页码:681 / 685
页数:5
相关论文
共 40 条
[11]  
Gripp S, 1998, CANCER-AM CANCER SOC, V83, P1495, DOI 10.1002/(SICI)1097-0142(19981015)83:8<1495::AID-CNCR4>3.3.CO
[12]  
2-F
[13]   CHILDHOOD MALIGNANT THYMOMA - CLINICAL, THERAPEUTIC, AND IMMUNOHISTOCHEMICAL CONSIDERATIONS [J].
KAPLINSKY, C ;
MOR, C ;
COHEN, IJ ;
GOSHEN, Y ;
YANIV, I ;
TAMARY, H ;
JABER, L ;
STARK, B ;
STERN, S ;
ZAIZOV, R .
PEDIATRIC HEMATOLOGY AND ONCOLOGY, 1992, 9 (03) :261-268
[14]  
KOH WJ, 1995, THYMONA ROLE RAD CHE, P1
[15]   PEDIATRIC THYMOMA - UNUSUAL OCCURRENCE IN 2 SIBLINGS [J].
LAM, WWM ;
CHAN, FL ;
LAU, YL ;
CHAU, MT ;
MOK, CK .
PEDIATRIC RADIOLOGY, 1993, 23 (02) :124-126
[16]   CISPLATIN PLUS DOXORUBICIN PLUS CYCLOPHOSPHAMIDE IN METASTATIC OR RECURRENT THYMOMA - FINAL RESULTS OF AN INTERGROUP TRIAL [J].
LOEHRER, PJ ;
KIM, K ;
AISNER, SC ;
LIVINGSTON, R ;
EINHORN, LH ;
JOHNSON, D ;
BLUM, R .
JOURNAL OF CLINICAL ONCOLOGY, 1994, 12 (06) :1164-1168
[17]   Cisplatin, doxorubicin, and cyclophosphamide plus thoracic radiation therapy for limited-stage unresectable thymoma: An intergroup trial [J].
Loehrer, PJ ;
Chen, M ;
Kim, KM ;
Aisner, SC ;
Einhorn, LH ;
Livingston, R ;
Johnson, D .
JOURNAL OF CLINICAL ONCOLOGY, 1997, 15 (09) :3093-3099
[18]  
MASAOKA A, 1981, CANCER, V48, P2485, DOI 10.1002/1097-0142(19811201)48:11<2485::AID-CNCR2820481123>3.0.CO
[19]  
2-R
[20]   THYMECTOMY AND MALIGNANCY [J].
MASAOKA, A ;
YAMAKAWA, Y ;
NIWA, H ;
FUKAI, I ;
SAITO, Y ;
TOKUDOME, S ;
NAKAHARA, K ;
FUJII, Y .
EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY, 1994, 8 (05) :251-253