Thymoma in children - Report of two cases and review of literature

被引:20
作者
Dhall, G [1 ]
Ginsburg, HB [1 ]
Bodenstein, L [1 ]
Fefferman, NR [1 ]
Greco, MA [1 ]
Chang, MW [1 ]
Gardner, S [1 ]
机构
[1] St Peters Univ Hosp, Div Pediat Hematol Oncol, New Brunswick, NJ 08903 USA
关键词
thymoma; children; nevus sebaceus;
D O I
10.1097/01.mph.0000141069.38462.d8
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Thymoma is an uncommon tumor of childhood. Stage of the tumor is an independent prognostic factor for survival. Surgery is the treatment of choice for stage 1 and stage 11 tumors. Chemotherapy is reserved for patients with refractory or metastatic disease. Thymomas are moderately radiosensitive. However, radiation therapy is not an attractive option for children due to its side-effects on developing organs. The authors describe 2 children with completely encapsulated thymoma who were successfully treated with Surgery alone. Both patients remain free of disease 3 years after Surgery. One of the patients also has nevus sebaceous. The authors also discuss the possible association between the two disease entities.
引用
收藏
页码:681 / 685
页数:5
相关论文
共 40 条
[1]  
AGHAJI MAC, 1990, CENT AFR J MED, V36, P263
[2]   Epidermal nevus syndrome with development of a mandibular ameloblastoma [J].
Bazopoulou-Kyrkanidou, E ;
Alexandridis, C ;
Tosios, KI ;
Sotiriadou, S ;
Angelopoulos, AP .
ORAL SURGERY ORAL MEDICINE ORAL PATHOLOGY ORAL RADIOLOGY AND ENDODONTOLOGY, 2000, 90 (01) :64-70
[3]   Unusual presentation of mycosis fungoides as pigmented purpura with malignant thymoma [J].
Cather, JC ;
Farmer, A ;
Jackow, C ;
Manning, JT ;
Shin, DM ;
Duvic, M .
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 1998, 39 (05) :858-863
[4]   EPIDERMAL NEVUS SYNDROME - REPORT OF ASSOCIATION WITH CHONDROBLASTOMA OF BONE [J].
CHOW, MJ ;
FRETZIN, DF .
PEDIATRIC DERMATOLOGY, 1989, 6 (04) :358-358
[5]   THYMUS RELATED TUMORS AND TUMOR-LIKE LESIONS IN CHILDHOOD WITH RAPID CLINICAL PROGRESSION AND DEATH [J].
DEHNER, LP ;
MARTIN, SA ;
SUMNER, HW .
HUMAN PATHOLOGY, 1977, 8 (01) :53-66
[6]  
Di Cataldo A, 2000, PEDIATR HEMAT ONCOL, V17, P701
[7]   EPIDERMAL NEVUS AND RHABDOMYOSARCOMA [J].
DIMOND, RL ;
AMON, RB .
ARCHIVES OF DERMATOLOGY, 1976, 112 (10) :1424-1426
[8]  
FURMAN WL, 1985, CANCER, V56, P2703, DOI 10.1002/1097-0142(19851201)56:11<2703::AID-CNCR2820561130>3.0.CO
[9]  
2-9
[10]  
Gharbi A, 1997, J RADIOL, V78, P303