Bridge to lung transplantation with the extracorporeal membrane ventilator Novalung in the veno-venous mode: The initial Hannover experience

被引:58
作者
Fischer, Stefan
Hoeper, Marius M.
Tomaszek, Sandra
Simon, Andre
Gottlieb, Jens
Welte, Tobias
Haverich, Axel
Strueber, Martin
机构
[1] Hannover Med Sch, Hannover Thorac Transplant Program, Div Thorac & Cardiovasc Surg, D-30625 Hannover, Germany
[2] Hannover Med Sch, Dept Resp Med, D-30625 Hannover, Germany
关键词
6;
D O I
10.1097/MAT.0b013e31802deb46
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
Conventional extracorporeal membrane oxygenation and mechanical ventilation have both been identified as significant risk factors for post-lung transplant mortality when applied as a bridge to lung transplantation. We have previously described the successful use of the extracorporeal membrane ventilator Novalung as a bridge to lung transplantation in patients with severe hypercapnia and respiratory acidosis. In this setting the Novalung was connected in the arterio-venous mode without support of a mechanical blood pump. However, in patients with predominant hypoxemia, this pumpless mode does not achieve sufficient blood oxygenation due to limited blood flow. Thus, such patients require pump-driven support. Here we describe our initial experience with the Novalung extracorporeal membrane ventilator, which was originally designed for pumpless carbon dioxide removal, as a bridge to lung transplantation in patients with ventilator-refractory hypoxemia in the veno-venous pump-driven mode.
引用
收藏
页码:168 / 170
页数:3
相关论文
共 6 条
  • [1] Extracorporeal membrane oxygenation (ECMO) for primary graft dysfunction (PGD) after lung transplantation: Analysis of the extracorporeal life support organisation (ELSO) registry
    Fischer, S.
    Bohn, D.
    Rycus, P.
    Pierre, A. F.
    de Perrot, M.
    Waddell, T. K.
    Keshavjee, S.
    [J]. JOURNAL OF HEART AND LUNG TRANSPLANTATION, 2006, 25 (02) : S124 - S124
  • [2] Bridge to lung transplantation with the novel pumpless interventional lung assist device NovaLung
    Fischer, S
    Simon, AR
    Welte, T
    Hoeper, MM
    Meyer, A
    Tessmann, R
    Gohrbandt, B
    Gottlieb, J
    Haverich, A
    Strueber, M
    [J]. JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY, 2006, 131 (03) : 719 - 723
  • [3] GATTINONI L, 1978, BRIT J ANAESTH, V50, P753, DOI 10.1093/bja/50.8.753
  • [4] Leukocyte adhesion dynamics in shear flow
    Simon, SI
    Goldsmith, HL
    [J]. ANNALS OF BIOMEDICAL ENGINEERING, 2002, 30 (03) : 315 - 332
  • [5] A polymethylpentene fiber gas exchanger for long-term extracorporeal life support
    Toomasian, JM
    Schreiner, RJ
    Meyer, DE
    Schmidt, ME
    Hagan, SE
    Griffith, GW
    Bartlett, RH
    Cook, KE
    [J]. ASAIO JOURNAL, 2005, 51 (04) : 390 - 397
  • [6] Registry of the International Society for Heart and Lung Transplantation: Twenty-second official adult lung and heart-lung transplant report - 2005
    Trulock, EP
    Edwards, LB
    Taylor, DO
    Boucek, MM
    Keck, BM
    Hertz, MI
    [J]. JOURNAL OF HEART AND LUNG TRANSPLANTATION, 2005, 24 (08) : 956 - 967